Evidence map›Paper›PMID 25453989›Full record

ArticlePsychiatry research2015

Fractional anisotropy in individuals with schizophrenia and their nonpsychotic siblings.

Michael P Harms, Kazi D Akhter, John G Csernansky, Susumu Mori, Deanna M Barch

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychiatry research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Diffusion-weighted imaging uncovers likely sources of processing-speed deficits in schizophrenia.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael P HarmsDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. Electronic address: mharms@wustl.edu.
Kazi D AkhterDepartment of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John G CsernanskyDepartment of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Susumu MoriDepartment of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Deanna M BarchDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; Department of Psychology, Washington University, St. Louis, MO, USA.

Funding

X-LINKED ADRENOLEUKODYSTROPHYP41RR015241 · NCRR · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BARKER, PETER B · 2001 to 2011
$18.5M
STRUCTURE, FUNCTION AND COGNITION IN SCHIZOPHRENIAP50MH071616 · NIMH · WASHINGTON UNIVERSITY · PI BARCH, DEANNA · 2004 to 2008
$11.2M
NEUROMORPHOMETRY IN SCHIZOPHRENIA BY COMPUTER ALGORITHMR01MH056584 · NIMH · WASHINGTON UNIVERSITY · PI CSERNANSKY, JOHN G · 1998 to 2011
$4.2M
Continued Development and Maintenance of MriStudioR01NS084957 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MILLER, MICHAEL I, MORI, SUSUMU · 2013 to 2022
$3.6M
NCRR NIH HHS P41 RR015241NCRR NIH HHS RR015241NIMH NIH HHS MH056584NIMH NIH HHS MH071616NIMH NIH HHS P50 MH071616NIMH NIH HHS R01 MH056584NINDS NIH HHS NS084957NINDS NIH HHS R01 NS084957
6 · The paper itself

Abstract

Fractional anisotropy (FA) was examined in a priori selected fiber tracts in individuals with schizophrenia (n=25) and their non-psychotic siblings (n=29) versus controls (n=35). FA was reduced in a portion of the fornix in individuals with schizophrenia (although this did not survive correction for the number of tracts investigated). FA in the siblings did not differ from that in controls in any of the investigated tracts.

Indexed as

AnisotropySiblingsAdultCase-Control StudiesDiffusion Tensor ImagingFemaleFornix, BrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleSchizophreniaDiffusion tensor imaging (DTI)EndophenotypeSchizophrenia

Identifiers

PMID25453989
PMCPMC4272646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.