Evidence map›Paper›PMID 25453425›Full record

ReviewClinics in chest medicine2014

Steroids for acute respiratory distress syndrome?

Catherine L Hough

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in Clinics in chest medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Update in COVID-19 2020.American journal of respiratory and critical care medicine · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Successful management of prolonged venovenous extracorporeal membrane oxygenation in an octogenarian.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2017
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Catherine L HoughDivision of Pulmonary and Critical Care Medicine, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Mailstop 359762, Seattle, WA 98104, USA. Electronic address: cterrlee@uw.edu.
University of Washington · US

Funding

RESPIRATORY RESEARCH TRAINING PROGRAMT32HL007287 · NHLBI · UNIVERSITY OF WASHINGTON · PI Kristina Anne Crothers, David J. Horne · 1985 to 2026
$16.7M
Critical Illness Polyneuropathy/Myopathy in ALIK23HL074294 · NHLBI · UNIVERSITY OF WASHINGTON · PI HOUGH, CATHERINE LEE · 2004 to 2008
$762k
CCTG CLINICAL NETWORK FOR ARDS TREATMENT--CRITICAL CAREN01HR046055 · HR · UNIVERSITY OF WASHINGTON · PI HUDSON, LEONARD D · 1994 to 2000
$468k
NHLBI NIH HHS K23 HL074294NHLBI NIH HHS N01 HR046055NHLBI NIH HHS T32 HL 007287NHLBI NIH HHS T32 HL007287
6 · The paper itself

Abstract

The development and severity of acute respiratory distress syndrome (ARDS) are closely related to dysregulated inflammation, and the duration of ARDS and eventual outcomes are related to persistent inflammation and abnormal fibroproliferation. Corticosteroids are potent modulators of inflammation and inhibitors of fibrosis that have been used since the first description of ARDS in attempts to improve outcomes. There is no evidence that corticosteroids prevent the development of ARDS among patients at risk. High-dose and short-course treatment with steroids does not improve the outcomes of patients with ARDS. Additional studies are needed to recommend treatment with steroids for ARDS.

Indexed as

Drug Administration ScheduleGlucocorticoidsHumansRespiratory Distress SyndromeGlucocorticoidsARDSCorticosteroidsOutcomesPreventionTreatment

Identifiers

PMID25453425
PMCPMC4297198
OpenAlexW2041162284

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.