ArticleAnnals of epidemiology2015
Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.
Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prenatal alcohol exposure and associations with physical size, dysmorphology and neurodevelopment: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- The Population-Attributable Fractions of Small-for-Gestational-Age Births: Results from the Japan Birth Cohort Consortium.Nutrients · 2024Pooled it
- Maternal smoking status during pregnancy and low birth weight in offspring: systematic review and meta-analysis of 55 cohort studies published from 1986 to 2020.World journal of pediatrics : WJP · 2022Pooled it
- Pooled it
- Gestational age and socioeconomic status as mediators for the impact of prenatal alcohol exposure on development at 6 months.Birth defects research · 2019Trial
- Prenatal alcohol use effects on birth, development, and educational outcomes in the Aboriginal and non-Aboriginal populations in the Northern Territory of Australia: a study protocol.BMC pregnancy and childbirth · 2025Article
- Prevalence of prenatal alcohol use among Aboriginal and non-Aboriginal women in the Northern Territory, Australia: estimate from perinatal, emergency, and admission datasets.BMC pregnancy and childbirth · 2025Article
- Clinical Features of Typically Developing Children with and without Prenatal Alcohol Exposure.The Journal of pediatrics · 2025Article
- Early Life Outcomes of Prenatal Exposure to Alcohol and Synthetic Cannabinoids in Mice.bioRxiv : the preprint server for biology · 2025Article
- The association between neighborhood environment, prenatal exposure to alcohol and tobacco, and structural brain development.Frontiers in human neuroscience · 2025Article
- Effects of Maternal HIV Infection and Alcohol Use in Pregnancy on Birth Outcomes in Uganda.AIDS and behavior · 2024Article
- The effect of possible mediators on the association between chewing khat during pregnancy and fetal growth and newborn size at birth in Eastern Ethiopia.BMC pregnancy and childbirth · 2024Article
- The relationship between small for gestational age infants and maternal health: a meta-analysis.American journal of translational research · 2024Review
- Alcohol exposure before and during pregnancy is associated with reduced fetal growth: the Safe Passage Study.BMC medicine · 2023Article
- Associations between prenatal alcohol and tobacco exposure on Doppler flow velocity waveforms in pregnancy: a South African study.BMC pregnancy and childbirth · 2023Article
- In utero and childhood exposure to alcohol and old age mortality: Evidence from the temperance movement in the US.Economics and human biology · 2023Article
- Metabolic risk factors and fertility disorders: A narrative review of the female perspective.Reproductive biomedicine & society online · 2022Review
- The effects of maternal alcohol consumption during pregnancy on adverse fetal outcomes among pregnant women attending antenatal care at public health facilities in Gondar town, Northwest Ethiopia: a prospective cohort study.Substance abuse treatment, prevention, and policy · 2021Article
- Maternal alcohol consumption and risk of offspring with congenital malformation: the Japan Environment and Children's Study.Pediatric research · 2021Article
- Association between maternal alcohol consumption during pregnancy and risk of preterm delivery: the Japan Environment and Children's Study.BJOG : an international journal of obstetrics and gynaecology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo estimate whether low-to-moderate prenatal alcohol exposure is associated with selected birth outcomes.
methodsLow-to-moderate prenatal alcohol drinking and effects on low birthweight, preterm delivery, intrauterine growth restriction, and selected neonatal outcomes were evaluated among 4496 women and singleton infants. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression, controlling for confounding variables.
resultsEarly pregnancy drinking was associated with reduced odds of low birthweight, OR, 0.66 (95% CI, 0.46-0.96) and birth length less than 10th percentile, OR, 0.74 (95% CI, 0.56-0.97). Drinking during the first 3 months showed lower odds for birth length and head circumference less than 10th percentile, OR, 0.56 (95% CI, 0.36-0.87) and OR, 0.69 (95% CI, 0.50-0.96), respectively. Third trimester drinking was associated with lower odds for low birthweight, OR, 0.56 (95% CI, 0.34-0.94) and preterm delivery, OR, 0.60 (95% CI, 0.42-0.87).
conclusionsOur results suggest low-to-moderate alcohol exposure during early and late gestation is not associated with increased risk of low birthweight, preterm delivery, intrauterine growth restriction, and most selected perinatal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.