ReviewFrontiers in behavioral neuroscience2014
Frontostriatal circuits and the development of bulimia nervosa.
Review in Frontiers in behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- The effects of neuromodulation interventions on the eating behaviors of patients with eating disorders compared to healthy controls, sham therapies, and other therapeutic approaches: A systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- Frontostriatal circuitry as a target for fMRI-based neurofeedback interventions: A systematic review.Frontiers in human neuroscience · 2022Pooled it
- Increased brain and behavioural susceptibility to portion size in children with loss of control eating.Pediatric obesity · 2019Trial
- Trial
- Bulimia nervosa.Nature reviews. Disease primers · 2026Review
- Neuropsychological and metabolic interconnectivity in obesity, anorexia and bulimia nervosa - an integrative literature review.Metabolic brain disease · 2026Review
- Non-invasive brain stimulation as an experimental treatment approach for bulimia nervosa and binge eating disorders: A meta-analysis and systematic review of literature.Indian journal of psychiatry · 2026Review
- Annual Research Review: Neural mechanisms of eating disorders in youth - from current theory and findings to future directions.Journal of child psychology and psychiatry, and allied disciplines · 2026Review
- Eating and Mental Health Disorders.Nutrients · 2026Article
- Preliminary Case Series of the Worth Warrior Mobile App for Young People With Low Self-Esteem and Mild Eating Disorders: Pre- and Post-Follow-Up Study.JMIR formative research · 2026Article
- Multimodal Investigations of Structural and Functional Brain Alterations in Anorexia and Bulimia Nervosa and Their Relationships to Psychopathology.Biological psychiatry · 2025Article
- Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Bulimia Nervosa (BN): A Review and Insight into Potential Mechanisms of Action.Journal of clinical medicine · 2024Review
- Why Don't You Just Eat? Neuroscience and the Enigma of Eating Disorders.Focus (American Psychiatric Publishing) · 2024Article
- Yoga as an adjunct treatment for eating disorders: a qualitative enquiry of client perspectives.BMC complementary medicine and therapies · 2024Article
- Therapeutic ketogenic diet as treatment for anorexia nervosa.Frontiers in nutrition · 2024Review
- Severe-Enduring Anorexia Nervosa (SE-AN): a case series.Journal of eating disorders · 2023Article
- Alterations of interhemispheric functional homotopic connectivity and corpus callosum microstructure in bulimia nervosa.Quantitative imaging in medicine and surgery · 2023Article
- Central Regulation of Eating Behaviors in Humans: Evidence from Functional Neuroimaging Studies.Nutrients · 2023Review
- Binge-Eating Precursors in Children and Adolescents: Neurodevelopment, and the Potential Contribution of Ultra-Processed Foods.Nutrients · 2023Review
- A framework for conceptualising early intervention for eating disorders.European eating disorders review : the journal of the Eating Disorders Association · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Bulimia nervosa (BN) is characterized by both recurrent episodes of binge eating that are, in part, defined by a sense of loss of control and compensatory behaviors to avoid weight gain. Impulsive behaviors are also common in individuals with BN, indicating more pervasive difficulties in behavioral self-regulation. Findings from functional and anatomical neuroimaging studies of individuals with BN suggest dysfunction in the dorsal frontostriatal circuits that support self-regulatory capacities and habit learning and in overlapping ventral circuits that support reward processing and reward-based learning. In this review, we describe the normal development of frontostriatal circuits and then present behavioral and neuroimaging data from adolescents and adults with BN. These data suggest that the abnormal maturation of frontostriatal circuits may contribute to the habitual binge-eating and purging behaviors of BN. Future longitudinal imaging studies will improve understanding of how these circuits contribute to the developmental trajectory of BN and will inform novel interventions that could target or prevent the impulsive and habit-like features of this disorder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.