Evidence map›Paper›PMID 25452661›Full record

ReviewPediatrics in review2014

Respiratory syncytial virus infection and bronchiolitis.

Giovanni Piedimonte, Miriam K Perez

Erratum issued Registry-linked trialAbstract readReview
In one paragraph

Review in Pediatrics in review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06267118 (A Randomized Controlled Trial on the Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis in Children), which is not on this map. Cited by 177 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
177citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06267118 phase3recruitingnot on this mapstarted 2023, after this paper: background citation

A Randomized Controlled Trial on the Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis in Children

TypeinterventionalSponsorCombined Military Hospital, PakistanRan2023 to 2024Enrolled60ConditionsAcute Bronchiolitis Due to Respiratory Syncytial VirusArmsHypertonic Saline Solution, 1 Ml, Adrenaline
3 · Its place in the literature

Who cites it

177 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Frontiers in immunology · 2021
    Pooled it
  8. Pooled it
  9. Systematic review on respiratory syncytial virus epidemiology in adults and the elderly in Latin America.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Observational
  15. Early-life respiratory syncytial virus infection and asthma.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  16. Article
  17. Imaging of pediatric pulmonary infections: A pictorial review.World journal of clinical pediatrics · 2026
    Review
  18. Respiratory syncytial virus - from discovery to vaccines.Journal of medical microbiology · 2026
    Review
  19. Article
  20. Article

117 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Giovanni PiedimonteCleveland Clinic Pediatric Institute, Cleveland, OH. Cleveland Clinic Children's Hospital for Rehabilitation, The Cleveland Clinic, Cleveland, OH.
Miriam K PerezCleveland Clinic Pediatric Institute, Cleveland, OH. Department of Community Pediatrics, Independence Family Health Center, Independence, OH.

Funding

NEUROGENIC INFLAMMATORY RESPONSE TO RSVR01HL061007 · NHLBI · WEST VIRGINIA UNIVERSITY · PI PIEDIMONTE, GIOVANNI · 1999 to 2022
$7.2M
NHLBI NIH HHS HL-061007NHLBI NIH HHS R01 HL061007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bronchiolitis, ViralHumansRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsViral VaccinesViral Vaccines

Identifiers

PMID25452661
PMCPMC5029757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.