ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015
Disseminated, persistent, and fatal infection due to the vaccine strain of varicella-zoster virus in an adult following stem cell transplantation.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 68 citations in OpenAlex.
- Acyclovir Prophylaxis Reduces the Incidence of Herpes Zoster Among HIV-Infected Individuals: Results of a Randomized Clinical Trial.The Journal of infectious diseases · 2016Trial
- Disseminated Varicella-Zoster Virus Infection with Internal Organ Involvement: A Scoping Review of 156 Cases.Viruses · 2025Article
- Antibody Responses Following Primary Immunization with the Recombinant Herpes Zoster Vaccine (ShingrixVaccines · 2025Article
- Research Progress on Varicella-Zoster Virus Vaccines.Vaccines · 2025Review
- A Review of Clinical Trials of Cancer and Its Treatment as a Vaccine.Reviews on recent clinical trials · 2024Review
- Vaccine schedule recommendations and updates for patients with hematologic malignancy post-hematopoietic cell transplant or CAR T-cell therapy.Transplant infectious disease : an official journal of the Transplantation Society · 2023Review
- Safety Surveillance of Varicella Vaccines in the Vaccine Adverse Event Reporting System, United States, 2006-2020.The Journal of infectious diseases · 2022Review
- Live Attenuated Varicella Vaccine: Prevention of Varicella and of Zoster.The Journal of infectious diseases · 2021Article
- Association of Achalasia With Active Varicella Zoster Virus Infection of the Esophagus.Gastroenterology · 2021Article
- Safety and reactogenicity of the recombinant zoster vaccine after allogeneic hematopoietic cell transplantation.Blood advances · 2021Observational
- [General principles of vaccination under immunosuppression].Zeitschrift fur Rheumatologie · 2020Review
- [Varicella vaccination and congenital immunodeficiency].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020Article
- JAK inhibitors and infections risk: focus on herpes zoster.Therapeutic advances in musculoskeletal disease · 2020Article
- Vaccine Oka Varicella Meningitis in Two Adolescents.Pediatrics · 2019Article
- Tale of two vaccines: differences in response to herpes zoster vaccines.The Journal of clinical investigation · 2018Article
- Is chickenpox so bad, what do we know about immunity to varicella zoster virus, and what does it tell us about the future?The Journal of infection · 2017Review
- Simultaneous Occurrence of Varicella Zoster Virus-Induced Pancreatitis and Hepatitis in a Renal Transplant Recipient: A Case Report and Review of Literature.The Permanente journal · 2017Review
- Epidemiology of Herpes Zoster Ophthalmicus: Recurrence and Chronicity.Ophthalmology · 2016Article
- Fatal disseminated varicella zoster infection following zoster vaccination in an immunocompromised patient.BMJ case reports · 2016Article
- THE JEREMIAH METZGER LECTURE VARICELLA ZOSTER VIRUS: FROM OUTSIDE TO INSIDE.Transactions of the American Clinical and Climatological Association · 2016Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Live attenuated varicella vaccine is recommended for healthy individuals who are susceptible to varicella. Although the vaccine is safe, effective, and used worldwide, serious adverse events have been reported, mainly in immunocompromised patients who subsequently recovered. Here, we describe the fatality of an immunocompromised patient who received the varicella vaccine. His medical history provides a cautionary lens through which to view the decision of when vaccination is appropriate. A middle-aged man with non-Hodgkin lymphoma received chemotherapy and a stem cell transplant. He was vaccinated 4 years post-transplantation, despite diagnosis of a new low-grade lymphoma confined to the lymph nodes. Within 3 months of vaccination, he developed recurrent rashes with fever, malaise, weakness, hepatitis, weight loss, and renal failure. The syndrome was eventually determined to be associated with persistent disseminated zoster caused by the vaccine virus. This case illustrates a circumstance when a live viral vaccine should not be used.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.