Evidence map›Paper›PMID 25452067›Full record

ArticleAddictive behaviors2015

Smoking history, and not depression, is related to deficits in detection of happy and sad faces.

K K Meyers, N A Crane, R O'Day, J K Zubieta, B Giordani, C S Pomerleau, J C Horowitz, S A Langenecker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addictive behaviors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

K K MeyersDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
N A CraneDepartment of Psychiatry, The University of Illinois at Chicago, USA.
R O'DayNicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI, USA.
J K ZubietaDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
B GiordaniDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
C S PomerleauDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA; Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI, USA.
J C HorowitzDepartment of Medicine, University of Michigan, Ann Arbor, MI, USA.
S A LangeneckerDepartment of Psychiatry, University of Michigan, Ann Arbor, MI, USA; Nicotine Research Laboratory, University of Michigan Department of Psychiatry, Ann Arbor, MI, USA. Electronic address: slangen@uic.edu.

Funding

TISSUE SPECIFIC /INDUCIBLE REGULATION RECEPTORS /TRANSGEP01MH042251 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WATSON, STANLEY J · 1987 to 2006
$8.3M
Training in the Neuroscience of Mental HealthT32MH067631 · NIMH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI RASENICK, MARK M. · 2004 to 2024
$4.8M
Mesenchymal Cell Fate Determination by Extracellular Matrix StiffnessR01HL105489 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY C · 2011 to 2015
$1.9M
Depression Subtypes: Cognition, Emotion, NeurophysiologyK23MH074459 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGENECKER, SCOTT A · 2008 to 2012
$643k
NHLBI NIH HHS R01 HL105489NIMH NIH HHS K23 MH074459NIMH NIH HHS MH074459NIMH NIH HHS P01 MH042251NIMH NIH HHS P01MH 42251NIMH NIH HHS T32 MH067631NIMH NIH HHS T32MH067631
6 · The paper itself

Abstract

introductionPrevious research has demonstrated that chronic cigarette smoking and major depressive disorder (MDD) are each associated with cognitive decrements. Further, these conditions co-occur commonly, though mechanisms in the comorbid condition are poorly understood. There may be distinct, additive, or overlapping factors underlying comorbid cigarette smoking and MDD. The present study investigated the impact of smoking and MDD on executive function and emotion processing.

methodsParticipants (N=198) were grouped by diagnostic category (MDD and healthy controls, HC) and smoking status (ever-smokers, ES and never-smokers, NS). Participants completed the Facial Emotion Perception Test (FEPT), a measure of emotional processing, and the parametric Go/No-go task (PGNG), a measure of executive function.

resultsFEPT performance was analyzed using ANCOVA with accuracy and reaction time as separate dependent variables. Repeated measures MANCOVA was conducted for PGNG with performance measure and task level as dependent variables. Analyses for each task included diagnostic and smoking group as independent variables, and gender was controlled for. Results for FEPT reveal that lower overall accuracy was found for ES relative to NS, though MDD did not differ from HC. Post-hoc analyses revealed that ES were poorer at identifying happy and sad, but not fearful or angry, faces. For PGNG, poorer performance was observed in MDD relative to HC in response time to Go targets, but there were no differences for ES and NS. Interaction of diagnosis and smoking group was not observed for performance on either task.

conclusionsThe results of this study provide preliminary evidence for distinctive cognitive decrements in smokers and individuals with depression.

Indexed as

Facial ExpressionHappinessAdultAnalysis of VarianceEmotionsFemaleHumansMajor Depressive DisorderMaleMichiganRetrospective StudiesSmokingVisual PerceptionDepressionEmotion processingExecutive functioningEx-smokersFacial affect perceptionSmoking

Identifiers

PMID25452067
PMCPMC4314430

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.