ArticleAddictive behaviors2015
The effect of combination oral contraceptives on smoking-related symptomatology during short-term smoking abstinence.
Article in Addictive behaviors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Use of hormonal contraceptives and smoking cessation: A preliminary report.Addictive behaviors · 2018Trial
- We must look beyond primary reinforcement to understand nicotine use in women.Frontiers in neuroendocrinology · 2026Review
- Contraceptive hormone ethinyl estradiol but not levonorgestrel modulates the role of reinforcer-enhancement in nicotine self-administration in ovary-intact female Sprague-Dawley rats.Neuropharmacology · 2025Article
- Acceptability of Hormonal Contraceptives as a Smoking Cessation Aid for Women of Reproductive Age: A Web-Based Cross-Sectional Survey.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Synthetic contraceptive hormones occlude the ability of nicotine to reduce ethanol consumption in ovary-intact female rats.Drug and alcohol dependence · 2023Article
- The importance of translationally evaluating steroid hormone contributions to substance use.Frontiers in neuroendocrinology · 2023Review
- Sex/Gender Differences in the Time-Course for the Development of Substance Use Disorder: A Focus on the Telescoping Effect.Pharmacological reviews · 2023Review
- The association between hormonal contraceptive use and smoking, negative affect, and cessation attempts in college females.Drug and alcohol dependence reports · 2022Article
- Natural and synthetic estrogens specifically alter nicotine demand and cue-induced nicotine seeking in female rats.Neuropharmacology · 2021Article
- Subjective response to intranasal nicotine administration in oral contraceptive users and naturally-cycling women.Addictive behaviors · 2019Article
- Oral Contraceptives and Cigarette Smoking: A Review of the Literature and Future Directions.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Review
- Addiction and Dopamine: Sex Differences and Insights from Studies of Smoking.Current opinion in behavioral sciences · 2018Article
- Hormonal contraceptive use in smokers: Prevalence of use and associations with smoking motives.Addictive behaviors · 2018Article
- Ovarian hormones, menstrual cycle phase, and smoking: a review with recommendations for future studies.Current addiction reports · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Although an estimated 25% of premenopausal smokers report using oral contraceptives (OC), little is known about how OC use may influence smoking cessation. The purpose of this study was to examine the difference in smoking-related symptomatology during acute smoking abstinence between women on a standardized combination OC (Tri-Sprintec(™)) compared to women not on OCs (no-OC). Participants were women aged 18-40 who smoked ≥5 cigarettes/day and reported regular menstrual cycles. Using a controlled cross-over design, participants completed two six-day testing weeks: Low Progesterone Week (LPW; Follicular (F) phase in no-OC or 1st week of pills in OC) and High Progesterone Week (HPW; Luteal (L) phase in no-OC or 3rd week of pills in OC). Each testing week included daily assessment of symptomatology and biochemical confirmation of smoking status. During smoking abstinence, the OC group (n=14) reported significantly lower levels of positive affect (21.56±7.12 vs. 24.57±6.46; β=3.63, p=0.0323) than the no-OC group (n=28). Further significant interactions between group and testing week were observed as follows: Smoking satisfaction was higher during LPW in the OC group (LPW: 4.29±1.30 vs. HPW: 4.10±1.37) but higher during HPW in the no-OC group (LPW: 3.91±1.30 vs. HPW: 4.23±1.30; β=-0.5499, p<0.0001). Similar interactions were noted in negative affect and psychological reward of smoking. These results suggest that women on OCs may have different patterns of smoking-related symptomatology during short-term smoking abstinence as compared to women not on OCs. Additional work is needed to examine how this may affect smoking cessation efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.