ArticleThe Journal of urology2015
Impact of real-time elastography on magnetic resonance imaging/ultrasound fusion guided biopsy in patients with prior negative prostate biopsies.
Article in The Journal of urology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical practice guidelines for ultrasound elastography: prostate.Journal of medical ultrasonics (2001) · 2016Guideline
- Development of ultrasonography for the detection of prostate cancer.Journal of medical ultrasonics (2001) · 2026Review
- A Scholte wave approach for ultrasonic surface acoustic wave elastography.Medical physics · 2023Article
- Reverberant magnetic resonance elastographic imaging using a single mechanical driver.Physics in medicine and biology · 2023Article
- Assessment of elastographic Q-analysis score combined with Prostate Imaging-Reporting and Data System (PI-RADS) based on transrectal ultrasound (TRUS)/multi-parameter magnetic resonance imaging (MP-MRI) fusion-guided biopsy in differentiating benign and malignant prostate.Quantitative imaging in medicine and surgery · 2022Article
- Application of Multiple Ultrasonic Techniques in the Diagnosis of Prostate Cancer.Frontiers in oncology · 2022Review
- Focal Prostate Stereotactic Body Radiation Therapy With Correlative Pathological and Radiographic-Based Treatment Planning.Frontiers in oncology · 2021Article
- Combining real-time elastography with fine-needle aspiration biopsy to identify malignant thyroid nodules.The Journal of international medical research · 2020Article
- Prostate cancer diagnosis and treatment using multiparametric transrectal ultrasonography.Journal of medical ultrasonics (2001) · 2019Article
- National Survey of Patterns Employing Targeted MRI/US Guided Prostate Biopsy in the Diagnosis and Staging of Prostate Cancer.Current urology · 2019Article
- Article
- Magnetic resonance imaging detection of prostate cancer in men with previous negative prostate biopsy.Translational andrology and urology · 2017Review
- Feasibility of a 2European radiology · 2017Article
- Article
- The detection of significant prostate cancer is correlated with the Prostate Imaging Reporting and Data System (PI-RADS) in MRI/transrectal ultrasound fusion biopsy.World journal of urology · 2016Article
- A Review of Imaging Methods for Prostate Cancer Detection.Biomedical engineering and computational biology · 2016Review
- Is magnetic resonance/ultrasound fusion prostate biopsy better than systematic prostate biopsy? An updated meta- and trial sequential analysis.Oncotarget · 2015Article
- Multiparametric magnetic resonance imaging for prostate cancer: A review and update for urologists.Korean journal of urology · 2015Review
- Endorectal fusion imaging: A description of a new technique.Endoscopic ultrasoundArticle
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe fusion of multiparametric resonance imaging and ultrasound has been proven capable of detecting prostate cancer in different biopsy settings. The addition of real-time elastography promises to increase the precision of the outcome of targeted biopsies. We investigated whether real-time elastography improves magnetic resonance imaging/transrectal ultrasound fusion targeted biopsy in patients after previous negative biopsies. MATERIALS AND
methodsProspectively 121 men underwent 3T magnetic resonance imaging. Using magnetic resonance imaging/real-time elastography fusion every suspicious lesion was characterized according to its tissue density and sampled by 2 fusion guided targeted biopsies. Additionally, all patients underwent 12-core systematic biopsy. The detection rate of clinically significant and insignificant cancers was compared between targeted und systematic biopsies. The accuracy to predict high grade prostate cancer was evaluated for with the PI-RADS scoring system and compared to the magnetic resonance imaging/real-time elastography fusion score.
resultsOverall prostate cancer was detected in 52 patients (43%). Targeted fusion guided biopsy revealed prostate cancer in 32 men (26.4%) and systematic biopsy in 46 (38%). The proportion of clinically significant cancers was higher for targeted biopsy (90.6%) compared to systematic biopsy (73.9%). The detection rate per core was higher for targeted biopsies (14.7%) compared to systematic biopsies (6.5%, p <0.001). The prediction of biopsy result according to magnetic resonance imaging/real-time elastography fusion was better (AUC 0.86) than magnetic resonance imaging alone (AUC 0.79). Sensitivity and specificity for magnetic resonance imaging/real-time elastography fusion was 77.8% and 77.3% vs 74.1% and 62.9% for magnetic resonance imaging.
conclusionsMagnetic resonance imaging/transrectal ultrasound fusion enhances the likelihood of detecting clinically significant cancers in a repeat biopsy setting. Adding real-time elastography to magnetic resonance imaging supports the characterization of cancer suspicious lesions.
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