ArticleGynecologic oncology2015
Perioperative blood transfusion in gynecologic oncology surgery: analysis of the National Surgical Quality Improvement Program Database.
Article in Gynecologic oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- How low should we go: A systematic review and meta-analysis of the impact of restrictive red blood cell transfusion strategies in oncology.Cancer treatment reviews · 2016Pooled it
- A prospective randomized controlled trial evaluating the safety and efficacy of patient blood management program in patients with gynecologic cancer (KGOG 4011/PBM).International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023Trial
- Transfusion use and effect on progression-free, overall survival, and quality of life in upfront treatment of advanced epithelial ovarian cancer: evaluation of the European Organization for Research and Treatment EORTC-55971 Cohort.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023Trial
- Trial
- First report of a combined hemostatic technique using Hydrofit® and SURGICEL Absorbable HemostatTM for intraoperative hemorrhage in gynecologic oncology surgery: a video article.Obstetrics & gynecology science · 2026Article
- Article
- Evaluation of Surgi-ORC for Hemostasis and Safety in Gynecological Surgeries: A Multicenter Prospective Observational Pilot Study.Obstetrics and gynecology international · 2026Article
- [Preoperative frailty and postoperative health outcomes in postmenopausal patients undergoing gynecological cancer surgery: a retrospective observational study].Journal of Korean biological nursing science · 2025Article
- Development and Validation of a Risk Model to Predict Intraoperative Blood Transfusion.JAMA network open · 2025Article
- Risk factors for blood transfusion in patients undergoing hysterectomy for stage I endometrial cancer.Langenbeck's archives of surgery · 2025Article
- Safe to save blood in ovarian cancer surgery - time to change transfusion habits.Acta oncologica (Stockholm, Sweden) · 2024Article
- Perioperative Blood Transfusions and Cancer Progression: A Narrative Review.Current oncology reports · 2024Review
- A pre-operative scoring model to estimate the risk of blood transfusion over an ovarian cancer debulking surgery (BLOODS score): a Memorial Sloan Kettering Cancer Center Team Ovary study.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Anemia in patients receiving anticancer treatments: focus on novel therapeutic approaches.Frontiers in oncology · 2024Review
- Impact of perioperative red blood cell transfusion on the prognosis of patients with epithelial ovarian cancer.Heliyon · 2023Article
- Article
- Characterization of pre-operative anemia in patients undergoing surgery by a gynecologic oncologist and association with post-operative complications.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023Article
- Stratification of Length of Stay Prediction following Surgical Cytoreduction in Advanced High-Grade Serous Ovarian Cancer Patients Using Artificial Intelligence; the Leeds L-AI-OS Score.Current oncology (Toronto, Ont.) · 2022Article
- Peri-operative blood management of Jehovah's Witnesses undergoing cytoreductive surgery for advanced ovarian cancer.Blood transfusion = Trasfusione del sangue · 2022Article
- Impact of perioperative red blood cell transfusion, anemia of cancer and global health status on the prognosis of elderly patients with endometrial and ovarian cancer.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo use a large-scale multi-institutional dataset to quantify the prevalence of packed red blood cell transfusions and examine the associations between transfusion and perioperative outcomes in gynecologic cancer surgery.
methodsThe American College of Surgeons National Surgical Quality Improvement Program (NSQIP) participant use file was queried for all gynecologic cancer cases between 2010 and 2012. Demographic, preoperative and intraoperative variables were compared between transfusion and non-transfusion groups using chi-squared, Fisher's exact and Wilcoxon rank-sum tests. The primary endpoint was 30-day composite morbidity. Secondary endpoints included composite surgical site infections, mortality and length of stay.
resultsA total of 8519 patients were analyzed, and 13.8% received a packed red blood cell transfusion. In the multivariate analysis, after adjusting for key clinical and perioperative factors, including preoperative anemia and case magnitude, transfusion was associated with higher composite morbidity (OR = 1.85, 95% CI 1.5-2.24), surgical site infections (OR 1.80, 95% CI 1.39-2.35), mortality (OR 3.38, 95% CI 1.80-6.36) and length of hospital stay (3.02 days v. 7.17 days, P < 0.001).
conclusionsBlood transfusions are associated with increased surgical wound infections, composite morbidity and mortality. Based on our analysis of the NSQIP database, transfusion practices in gynecologic cancer should be scrutinized. Examination of institutional practices and creation of transfusion guidelines for gynecologic malignancies could potentially result in better utilization of blood bank resources and clinical outcomes among patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.