Evidence map›Paper›PMID 25451442›Full record

ArticleJournal of affective disorders2015

Depression, anxiety and stress among pregnant migraineurs in a pacific-northwest cohort.

Olivia R Orta, Bizu Gelaye, Chungfang Qiu, Lee Stoner, Michelle A Williams

Abstract read
In one paragraph

Article in Journal of affective disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Migraine headache and depression in adults: a systematic Review and Meta-analysis.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2019
    Pooled it
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  16. Managing Migraine During Pregnancy and Lactation.Current neurology and neuroscience reports · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivia R OrtaDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, USA. Electronic address: oro109@mail.harvard.edu.
Bizu GelayeDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, USA.
Chungfang QiuCenter for Perinatal Studies, Swedish Medical Center, Seattle, WA, USA.
Lee StonerSchool of Sport and Exercise, College of Health, Massey University, Wellington, New Zealand.
Michelle A WilliamsDepartment of Epidemiology, Harvard School of Public Health, Boston, MA, USA.

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
Predoctoral Training Program in Reproductive, Perinatal & Pediatric EpidemiologyT32HD060454 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI MICHELS, KARIN B · 2010 to 2014
$1.1M
NICHD NIH HHS R01 HD059835NICHD NIH HHS R01‐HD‐059835NICHD NIH HHS T32 HD060454NICHD NIH HHS T32‐HD060454NIMHD NIH HHS T37 MD001449NIMHD NIH HHS T37-MD001449
6 · The paper itself

Abstract

backgroundThe co-occurrence of migraine and unipolar psychiatric disorders has been well documented in non-pregnant populations, however little is known in pregnant populations.

methodsA cohort of 1321 women was interviewed during the first trimester of pregnancy. At the time of interview lifetime migraine status was ascertained using International Classification of Headache Disorders diagnostic criteria (ICHD-II). Information regarding unipolar depression, anxiety and stress during pregnancy was collected using the Patient Health Questionnaire Depression Module-9 (PHQ-9), and the Depression Anxiety Stress Scales 21-item Short Form (DASS-21). Multivariable logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for the association of migraine and mood disorders during pregnancy.

resultsApproximately 28.2% (N=372) were classified as having a lifetime history of migraine; among migraineurs 122 were classified as migraineurs with aura and 250 as migraineurs without aura. Compared with non-migraineurs, migraineurs were associated with 1.60-fold increased odds of depression as measured by a PHQ-9 score ≥10 (AOR=1.60; 95% CI: 1.12-2.31). Overall, migraine with aura was more strongly associated with depression than was migraine without aura. Migraineurs, as compared with non-migraineurs, also had higher odds of mood disorders as measured by the DASS-21.

conclusionsThe comorbidity of mood and migraine disorders in pregnant populations supports the need for integrated mental and physical clinical evaluation, increased vigilance, and treatment of patients with such disorders.

Indexed as

AdultAnxietyAnxiety DisordersComorbidityDepressionDepressive DisorderFemaleHumansMaternal AgeMigraine with AuraMigraine without AuraNorthwestern United StatesOdds RatioPregnancyPregnancy ComplicationsPregnancy Trimester, FirstAnxietyDepressionMigrainePregnancyStress

Identifiers

PMID25451442
PMCPMC4406774

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.