Evidence map›Paper›PMID 25451049›Full record

ArticleAntimicrobial agents and chemotherapy2015

Susceptibility profiles of amphotericin B and posaconazole against clinically relevant mucorales species under hypoxic conditions.

Elisabeth Maurer, Ulrike Binder, Manuela Sparber, Michaela Lackner, Rita Caramalho, Cornelia Lass-Flörl

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Journal of fungi (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisabeth MaurerDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.
Ulrike BinderDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria ulrike.binder@i-med.ac.at.
Manuela SparberDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.
Michaela LacknerDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.
Rita CaramalhoDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.
Cornelia Lass-FlörlDivision of Hygiene and Medical Microbiology, Medical University Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of hypoxic conditions on the in vitro efficacy of amphotericin B and posaconazole against Mucorales was evaluated by defining MICs with Etest and broth microdilution and identifying minimal fungicidal concentrations (MFCs). With Etest, oxygen-dependent changes were detected, while the MIC and the MFC determined with broth microdilution remained unaltered with reduced oxygen levels. The observed differences depended on the method used.

Indexed as

Amphotericin BAntifungal AgentsCell HypoxiaMicrobial Sensitivity TestsMucoralesTriazolesAmphotericin BAntifungal AgentsposaconazoleTriazoles

Identifiers

PMID25451049
PMCPMC4335829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.