Evidence map›Paper›PMID 25450495›Full record

SynthesisPreventive medicine2014

Cultural relevance in medication adherence interventions with underrepresented adults: systematic review and meta-analysis of outcomes.

Vicki S Conn, Maithe Enriquez, Todd M Ruppar, Keith C Chan

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Preventive medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Observational
  10. Article
  11. Observational
  12. Peers as Facilitators of Medication Adherence Interventions: A Review.Journal of primary care & community health · 2016
    Review
  13. Peers Keep It Real: Re-engaging Adults in HIV Care.Journal of the International Association of Providers of AIDS Care
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vicki S ConnSinclair School of Nursing, University of Missouri, Columbia, MO 65211, USA. Electronic address: conn@missouri.edu.
Maithe EnriquezSinclair School of Nursing, University of Missouri, Columbia, MO 65211, USA. Electronic address: enriquezm@missouri.edu.
Todd M RupparSinclair School of Nursing, University of Missouri, Columbia, MO 65211, USA. Electronic address: ruppart@missouri.edu.
Keith C ChanSinclair School of Nursing, University of Missouri, Columbia, MO 65211, USA. Electronic address: chankc@missouri.edu.

Funding

Meta-Analysis of Interventions to Improve Medication AdherenceR01NR011990 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI CONN, VICKI S · 2010 to 2013
$1.7M
Peers keep it real: reaching 100% adherence to HIV treatmentK01NR014409 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI ENRIQUEZ, MAITHE · 2013 to 2015
$276k
NINR NIH HHS K01 NR014409NINR NIH HHS R01 NR011990NINR NIH HHS R01NR011990
6 · The paper itself

Abstract

objectiveThis meta-analysis systematically compiles intervention research designed to increase medication adherence among underrepresented adults.

methodComprehensive searching located published and unpublished studies with medication adherence behavior outcomes. Studies were included if samples were adults living in North America who had any of the following backgrounds or identities: African American, Native American, Latino, Latino American, Asian, Asian American, Pacific Islander, Native Alaskan, or Native Hawaiian. Random-effect analyses synthesized data to calculate effect sizes as a standardized mean difference and variability measures. Exploratory moderator analyses examined the association between specific efforts to increase the cultural relevance of medication adherence studies and behavior outcomes.

resultsData were synthesized across 5559 subjects in 55 eligible samples. Interventions significantly improved medication adherence behavior of treatment subjects compared to control subjects (standardized mean difference=0.211). Primary studies infrequently reported strategies to enhance cultural relevance. Exploratory moderator analyses found no evidence that associated cultural relevance strategies with better medication adherence outcomes.

conclusionThe modest magnitude of improvements in medication adherence behavior documents the need for further research with clear testing of cultural relevance features.

Indexed as

Drug MonitoringAdultAgedEthnicityFemaleHumansIndians, North AmericanMaleMedication AdherenceMiddle AgedMinority GroupsNorth AmericaPrescription DrugsVulnerable PopulationsPrescription DrugsMedication adherenceMeta-analysisMinority groups

Identifiers

PMID25450495
PMCPMC4312199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.