ArticleNeuroImage2015
A comparative analysis of mouse and human medial geniculate nucleus connectivity: a DTI and anterograde tracing study.
Article in NeuroImage, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- A conserved pulvinar projection to the amygdala revealed in macaque monkeys (Macaca mulatta).Brain structure & function · 2026Article
- A Direct Auditory Subcortical Route to the Amygdala Associated with Fear in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Article
- Long-term impact of white matter hyperintensities and amyloid beta on thalamic subregions in cerebral small vessel disease: A prospective cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Review
- Cerebral cortex functional reorganization in preschool children with congenital sensorineural hearing loss: a resting-state fMRI study.Frontiers in neurology · 2024Article
- A phylogenetically-conserved axis of thalamocortical connectivity in the human brain.Nature communications · 2023Article
- Towards reliable reconstruction of the mouse brain corticothalamic connectivity using diffusion MRI.NeuroImage · 2023Article
- Relay and higher-order thalamic nuclei show an intertwined functional association with cortical-networks.Communications biology · 2022Article
- Volumetric analysis of the aging auditory pathway using high resolution magnetic resonance histology.Frontiers in aging neuroscience · 2022Article
- Excitatory Repetitive Transcranial Magnetic Stimulation Over Prefrontal Cortex in a Guinea Pig Model Ameliorates Tinnitus.Frontiers in neuroscience · 2021Article
- Auditory fear conditioning alters neural gain in the cochlear nucleus: a wireless neural recording study in freely behaving rats.Neuronal signaling · 2020Article
- Variability and heritability of mouse brain structure: Microscopic MRI atlases and connectomes for diverse strains.NeuroImage · 2020Article
- Visualising the topography of the acoustic radiation in clinical diffusion tensor imaging scans.Neuroradiology · 2020Article
- Reciprocal connectivity between secondary auditory cortical field and amygdala in mice.Scientific reports · 2019Article
- Damage of the lateral geniculate nucleus in MS: Assessing the missing node of the visual pathway.Neurology · 2019Article
- Article
- Dissociation between Cerebellar and Cerebral Neural Activities in Humans with Long-Term Bilateral Sensorineural Hearing Loss.Neural plasticity · 2019Article
- Towards Differential Connectomics with NeuroVIISAS.Neuroinformatics · 2019Article
- When tractography meets tracer injections: a systematic study of trends and variation sources of diffusion-based connectivity.Brain structure & function · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Understanding the function and connectivity of thalamic nuclei is critical for understanding normal and pathological brain function. The medial geniculate nucleus (MGN) has been studied mostly in the context of auditory processing and its connection to the auditory cortex. However, there is a growing body of evidence that the MGN and surrounding associated areas ('MGN/S') have a diversity of projections including those to the globus pallidus, caudate/putamen, amygdala, hypothalamus, and thalamus. Concomitantly, pathways projecting to the medial geniculate include not only the inferior colliculus but also the auditory cortex, insula, cerebellum, and globus pallidus. Here we expand our understanding of the connectivity of the MGN/S by using comparative diffusion weighted imaging with probabilistic tractography in both human and mouse brains (most previous work was in rats). In doing so, we provide the first report that attempts to match probabilistic tractography results between human and mice. Additionally, we provide anterograde tracing results for the mouse brain, which corroborate the probabilistic tractography findings. Overall, the study provides evidence for the homology of MGN/S patterns of connectivity across species for understanding translational approaches to thalamic connectivity and function. Further, it points to the utility of DTI in both human studies and small animal modeling, and it suggests potential roles of these connections in human cognition, behavior, and disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.