Evidence map›Paper›PMID 25448244›Full record

Trial reportArchives of physical medicine and rehabilitation2015

Improving motor control in walking: a randomized clinical trial in older adults with subclinical walking difficulty.

Jennifer S Brach, Kristin Lowry, Subashan Perera, Victoria Hornyak, David Wert, Stephanie A Studenski, Jessie M VanSwearingen

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Archives of physical medicine and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
12.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01076413 nacompletednot on this map

Comparison of Two Exercise Interventions to Improve Gait in Older Persons: The PRIME (Program to Improve Mobility in The Elderly) Study

TypeinterventionalSponsorUniversity of PittsburghRan2010 to 2012Enrolled40ConditionsGaitArmsskill based exercise, aerobic conditioning
NCT03737331 naterminatednot on this mapstarted 2018, after this paper: background citation

Variable Visual Stimulus as a Novel Approach for Gait Rehabilitation

TypeinterventionalSponsorUniversity of NebraskaRan2018 to 2019Enrolled1ConditionsGait Disorders, NeurologicArmsFractal visual cueing, Periodic visual cueing, Random visual cueing
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
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  7. Role of Walking Energetics and Perceived Fatigability Differs by Gait Speed: The Study of Muscle, Mobility and Aging (SOMMA).The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  8. Review
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  10. The Live Long Walk Strong Rehabilitation Program Study: Design and Methods.Archives of rehabilitation research and clinical translation · 2022
    Article
  11. Article
  12. Article
  13. Acceleration Gait Measures as Proxies for Motor Skill of Walking: A Narrative Review.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jennifer S BrachDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA. Electronic address: jbrach@pitt.edu.
Kristin LowryDepartment of Physical Therapy, Des Moines University, Des Moines, IA.
Subashan PereraDivision of Geriatric Medicine, University of Pittsburgh, Pittsburgh, PA.
Victoria HornyakDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.
David WertDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.
Stephanie A StudenskiLongitudinal Studies Section, National Institute on Aging, Baltimore, MD.
Jessie M VanSwearingenDepartment of Physical Therapy, University of Pittsburgh, Pittsburgh, PA.
University of Pittsburgh · USDes Moines University · USNational Institute on Aging · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
Pitt Integrated Clinical and Geroscience Research Training ProgramT32AG021885 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Aditi U Gurkar · 2003 to 2026
$6.7M
Gait Variability: Epidemiology, Assessment &ManagementK23AG026766 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BRACH, JENNIFER S · 2005 to 2009
$775k
NCATS NIH HHS UL1 TR000005NIA NIH HHS K23 AG026766NIA NIH HHS P30 AG024827NIA NIH HHS T32 AG021885
6 · The paper itself

Abstract

objectiveTo test the proposed mechanism of action of a task-specific motor learning intervention by examining its effect on measures of the motor control of gait.

designSingle-blinded randomized clinical trial.

settingUniversity research laboratory.

participantsAdults (N=40) aged ≥65 years with gait speed >1.0m/s and impaired motor skill (figure-of-8 walk time >8s).

interventionsThe 2 interventions included a task-oriented motor learning and a standard exercise program; both interventions included strength training. Both lasted 12 weeks, with twice-weekly, 1-hour, physical therapist-supervised sessions.

main outcome measuresTwo measures of the motor control of gait, gait variability and smoothness of walking, were assessed pre- and postintervention by assessors masked to the treatment arm.

resultsOf 40 randomized subjects, 38 completed the trial (mean age ± SD, 77.1±6.0y). The motor learning group improved more than the standard group in double-support time variability (.13m/s vs .05m/s; adjusted difference [AD]=.006, P=.03). Smoothness of walking in the anteroposterior direction improved more in the motor learning than standard group for all conditions (usual: AD=.53, P=.05; narrow: AD=.56, P=.01; dual task: AD=.57, P=.04). Smoothness of walking in the vertical direction also improved more in the motor learning than standard group for the narrow-path (AD=.71, P=.01) and dual-task (AD=.89, P=.01) conditions.

conclusionsAmong older adults with subclinical walking difficulty, there is initial evidence that task-oriented motor learning exercise results in gains in the motor control of walking, while standard exercise does not. Task-oriented motor learning exercise is a promising intervention for improving timing and coordination deficits related to mobility difficulties in older adults, and needs to be evaluated in a definitive larger trial.

Indexed as

Mobility LimitationAgedExercise TherapyFemaleHumansMaleMotor SkillsResistance TrainingSingle-Blind MethodTreatment OutcomeWalkingAgingExerciseGaitMotor controlRehabilitation

Identifiers

PMID25448244
PMCPMC4850731
OpenAlexW1995283275

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.