Evidence map›Paper›PMID 25448091›Full record

ArticleVaccine2015

Vaccine schedule compliance among very low birth weight infants in Lima, Peru.

Theresa J Ochoa, Alonso Zea-Vera, Rossana Bautista, Carmen Davila, José Antonio Salazar, Carlos Bazán, Luis López, Lucie Ecker

Abstract read
In one paragraph

Article in Vaccine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  14. Article
  15. Unintended pregnancy and its impact on childhood rotavirus immunization in Peru.Revista panamericana de salud publica = Pan American journal of public health · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Theresa J OchoaUniversidad Peruana Cayetano Heredia, Lima, Lima, Peru; University of Texas School of Public Health, Houston, TX, United States. Electronic address: Theresa.J.Ochoa@uth.tmc.edu.
Alonso Zea-VeraUniversidad Peruana Cayetano Heredia, Lima, Lima, Peru.
Rossana BautistaHospital Nacional Edgardo Rebagliati Martins, Lima, Lima, Peru.
Carmen DavilaInstituto de Nacional Materno Perinatal, Lima, Lima, Peru.
José Antonio SalazarHospital Guillermo Almenara Irigoyen, Lima, Lima, Peru.
Carlos BazánHospital Nacional Madre Niño San Bartolome, Lima, Lima, Peru.
Luis LópezInstituto de Nacional Materno Perinatal, Lima, Lima, Peru.
Lucie EckerInstituto de Investigación Nutricional, Lima, Lima, Peru.
Instituto Nacional de Salud del Niño · PEUniversidad Peruana Cayetano Heredia · PEHospital Base Guillermo Almenara Irigoyen · PEHospital Nacional Cayetano Heredia · PEInstituto de Investigación Nutricional · PE

Funding

Lactoferrin for prevention of sepsis in infantsR01HD067694 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI OCHOA, THERESA J · 2011 to 2015
$2.0M
NICHD NIH HHS R01 HD067694
6 · The paper itself

Abstract

objectiveThere is little information about vaccine schedule compliance in very-low-birth-weight infants in developing countries. The aim of the study was to describe the compliance with the vaccine schedule among this population in Lima, Peru. PATIENTS AND

methodsWe conducted a prospective cohort study in four hospitals in Lima in infants with a birth-weight of less than 1500 g, followed from birth up to 12 months of age every 2 weeks. The date and age at administration of each vaccine was recorded

results222 infants were enrolled. The median birth-weight was 1250 g (range 550-1499 g) and the median gestational age was 30.0 weeks (range 23-37 weeks). The mean age for the first pentavalent (DPT, Hib, HepB) and oral polio vaccine administration was 4.3 ± 1.4 months in infants with a birth-weight of < 1000 g vs. 3.1 ± 1.0 in infants with a birth-weight 1000-1500 g (p < 0.001); 4.1 ± 0.9 vs. 3.3 ± 1.1 for rotavirus (p < 0.05); and 5.1 ± 2.1 vs. 4.3 ± 1.8 for the 7-valent pneumococcal conjugated vaccine. Only 35% had received the three doses of oral polio and pentavalent vaccine by seven months, although by nine months 81% had received these vaccines.

conclusionsVaccination of very-low-birth-weight infants in Peru is significantly delayed, especially in infants with a birth-weight of < 1000 g and lower gestational age. Urgent educational interventions targeting physicians and nurses should be implemented in order to improve vaccination rates and timing in these high risk populations.

Indexed as

Guideline AdherenceImmunization ScheduleInfant, Very Low Birth WeightCohort StudiesDiphtheria-Tetanus-Pertussis VaccineFemaleGestational AgeHaemophilus VaccinesHumansInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesMalePeruPneumococcal VaccinesDiphtheria-Tetanus-Pertussis VaccineHaemophilus VaccinesPneumococcal VaccinesPoliovirus Vaccine, OralVaccinesVaccines, CombinedVaccines, ConjugateDeveloping countriesVaccinesVery low birth weight infant

Identifiers

PMID25448091
PMCPMC4320121
OpenAlexW2082904385

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.