Observational studyIntensive care medicine2015
Volume expansion in the first 4 days of shock: a prospective multicentre study in 19 French intensive care units.
Observational study in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02645851 (RApid Fluid Volume EXpansion), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
RApid Fluid Volume EXpansion (RVE) in Critically Ill Patients With Acute Circulatory Failure After the Initial Phase of Resuscitation. A Single-center, Open-label, Randomized Study Comparing 3 Strategies of RVE in Orléans, France.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Impact of hemodynamic goal-directed resuscitation on mortality in adult critically ill patients: a systematic review and meta-analysis.Journal of clinical monitoring and computing · 2018Pooled it
- Unnecessary fluid therapy in patients with shock: Five classic fluid pitfalls and five ways to do it better.Annals of intensive care · 2026Review
- Article
- Averaged versus Persistent Reduction in Urine Output to Define Oliguria in Critically Ill Patients: An Observational Study.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
- Effect of volume infusion on left atrial strain in acute circulatory failure.Annals of intensive care · 2024Article
- Easy method to determine fluid responsiveness in septic shock patients: end-tidal CO2 - a prospective observational study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Observational
- Physicians' Clinical Behavior During Fluid Evaluation Encounters.Critical care explorations · 2023Article
- An email-based survey of practice regarding hemodynamic monitoring and management in children with septic shock in China.Translational pediatrics · 2021Article
- Measurement site of inferior vena cava diameter affects the accuracy with which fluid responsiveness can be predicted in spontaneously breathing patients: a post hoc analysis of two prospective cohorts.Annals of intensive care · 2020Article
- Haemodynamic monitoring of COVID-19 patients: Classical methods and new paradigms.Anaesthesia, critical care & pain medicine · 2020Article
- Variation in Fluid and Vasopressor Use in Shock With and Without Physiologic Assessment: A Multicenter Observational Study.Critical care medicine · 2020Observational
- Characteristics of resuscitation, and association between use of dynamic tests of fluid responsiveness and outcomes in septic patients: results of a multicenter prospective cohort study in Argentina.Annals of intensive care · 2020Article
- How to detect a positive response to a fluid bolus when cardiac output is not measured?Annals of intensive care · 2019Article
- Time course of fluid responsiveness in sepsis: the fluid challenge revisiting (FCREV) study.Critical care (London, England) · 2019Observational
- Intravenous fluid therapy in critically ill adults.Nature reviews. Nephrology · 2018Review
- End-expiratory occlusion maneuver to predict fluid responsiveness in the intensive care unit: an echocardiographic study.Critical care (London, England) · 2018Article
- Focus on fluid therapy.Intensive care medicine · 2017Article
- Understanding oliguria in the critically ill.Intensive care medicine · 2017Article
- Fluid management in acute kidney injury.Intensive care medicine · 2017Review
- Crystalloid Fluid Choice and Clinical Outcomes in Pediatric Sepsis: A Matched Retrospective Cohort Study.The Journal of pediatrics · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 15 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo describe the current practices of volume expansion in French intensive care units (ICU).
methodsIn 19 ICUs, we prospectively observed the prescription and monitoring practices of volume expansion in consecutive adult patients with shock [sustained hypotension and/or need of vasopressor therapy, associated with at least tachycardia and/or sign (s) of hypoperfusion]. Patients were included at the time of prescription of the first fluid bolus (FB). Thereafter, all the FBs administered during the 96 h following shock onset were surveyed. An FB was defined as an intravenous bolus of at least 100 ml of a blood volume expander intended to rapidly improve the patient's circulatory condition.
resultsWe included 777 patients [age: 63 ± 15 years; female gender: 274 (35 %); simplified acute physiology score II: 55.9 ± 20.6; ICU length of stay: 6 days (interquartile range (IQR) 3-13); ICU mortality: 32.8 %] and surveyed 2,694 FBs. At enrolment mean arterial pressure was 63 mmHg (IQR 55-71). The most frequent triggers of FB were hypotension, low urine output, tachycardia, skin mottling and hyperlactataemia. Amount of fluid given at each FB was highly variable between centres. Crystalloids were used in 91 % (2,394/2,635) and synthetic colloids in 3.3 % (87/2,635) of FBs. Overall, clinicians used any kind of haemodynamic assessment (central venous pressure measurement, predictive indices of fluid responsiveness, echocardiography, cardiac output monitoring or a combination of these) in 23.6 % (635/2,694) of all FBs surveyed, with an important between-centre heterogeneity.
conclusionsHigh between-centre variability characterised all the aspects of FB prescription and monitoring, but overall haemodynamic exploration to help guide and monitor FB was infrequent.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.