Evidence map›Paper›PMID 25447334›Full record

Trial reportPhysiology & behavior2015

A pilot randomized trial of a cognitive reappraisal obesity prevention program.

Eric Stice, Sonja Yokum, Kyle Burger, Paul Rohde, Heather Shaw, Jeff M Gau

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiology & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03557710 (Devaluing Energy-dense Foods for Cancer-control), which is not on this map. Cited by 30 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03557710 nacompletednot on this mapstarted 2018, after this paper: background citation

Devaluing Energy-dense Foods for Cancer-control: Translational Neuroscience

TypeinterventionalSponsorUniversity of OregonRan2018 to 2023Enrolled253ConditionsOverweight and Obesity, CancerArmsDevaluing energy-dense foods for cancer-control
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Interventions for preventing obesity in children.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
    Pooled it
  5. Effects of total fat intake on bodyweight in children.The Cochrane database of systematic reviews · 2018
    Pooled it
  6. Food cue reactivity and craving predict eating and weight gain: a meta-analytic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2016
    Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
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  13. Article
  14. Article
  15. Food Attention Bias: appetite comes with eating.Journal of eating disorders · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Regulation of Craving and Negative Emotion in Alcohol Use Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eric SticeOregon Research Institute, United States. Electronic address: estice@ori.org.
Sonja YokumOregon Research Institute, United States.
Kyle BurgerUniversity of North Carolina at Chapel Hill, United States.
Paul RohdeOregon Research Institute, United States.
Heather ShawOregon Research Institute, United States.
Jeff M GauOregon Research Institute, United States.

Funding

Effectiveness Trial of a Dissonance-Based Obesity Prevention ProgramR01HD071900 · NICHD · OREGON RESEARCH INSTITUTE · PI STICE, ERIC M · 2012 to 2016
$2.9M
NICHD NIH HHS R01 HD071900
6 · The paper itself

Abstract

BACKGROUND/

objectivesEvaluate a selective obesity prevention program promoting use of cognitive reappraisals to reduce reward region response and increase inhibitory region response to high-fat/high-sugar foods and reduce intake of fat and sugar to prevent blunted reward region response to intake of such foods. SUBJECTS/

methodsYoung adults at risk for future weight gain by virtue of weight concerns (N=148) were randomized to this new prevention program (Minding Health), an alternative prevention program promoting participant-driven gradual reductions in caloric intake and increases in physical activity (Healthy Weight), or an obesity education video control condition, completing assessments at pre-, post-, and 6-month follow-up. A subset of Minding Health and control participants completed an fMRI scan at pre- and post-assessing neural response to images of high-fat/sugar foods and to receipt and anticipated receipt of a high-fat/sugar food.

resultsMinding Health participants showed significantly greater reductions in body fat than controls and caloric intake from fat and sugar than Healthy Weight participants. Minding Health participants also showed greater activation of an inhibitory control region and reduced activation of an attention/expectation region in response to palatable food images relative to pretest and controls. However, Healthy Weight participants showed greater reductions in BMI and eating disorder symptoms than Minding Health participants.

conclusionsAlthough the Minding Health intervention produced some of the hypothesized effects, it did not produce lasting reductions in body fat or BMI and showed limited effects on neural responsivity, implying it will be vital to increase the efficacy of this new prevention program.

Indexed as

Adipose TissueBody Mass IndexBrainBrain MappingCognitionCognitive Behavioral TherapyFeeding BehaviorFemaleFollow-Up StudiesFoodHumansMagnetic Resonance ImagingMaleObesityPhotic StimulationPilot ProjectsfMRIInhibitory regionsObesityPreventionReward regionsWeight gain

Identifiers

PMID25447334
PMCPMC4258533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.