Evidence map›Paper›PMID 25447000›Full record

ReviewThe Journal of hand surgery2015

The quality of control groups in nonrandomized studies published in the Journal of Hand Surgery.

Shepard P Johnson, Sunitha Malay, Kevin C Chung

Abstract readReview
In one paragraph

Review in The Journal of hand surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shepard P JohnsonDepartment of Surgery, Saint Joseph Mercy Hospital, Ann Arbor, MI; Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI; Section of Plastic Surgery, University of Michigan Medical School, Ann Arbor, MI.
Sunitha MalayDepartment of Surgery, Saint Joseph Mercy Hospital, Ann Arbor, MI; Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI; Section of Plastic Surgery, University of Michigan Medical School, Ann Arbor, MI.
Kevin C ChungDepartment of Surgery, Saint Joseph Mercy Hospital, Ann Arbor, MI; Section of Plastic Surgery, Department of Surgery, University of Michigan Health System, Ann Arbor, MI; Section of Plastic Surgery, University of Michigan Medical School, Ann Arbor, MI. Electronic address: kecchung@umich.edu.

Funding

A Clinical Trial for the Surgical Treatment of Elderly Distal Radius FracturesR01AR062066 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHUNG, KEVIN C · 2011 to 2016
$3.8M
An Outcome Study of Rheumatoid Hand ArthroplastyR01AR047328 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHUNG, KEVIN C · 2003 to 2016
$3.1M
Evidence-Based Research in Hand SurgeryK24AR053120 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHUNG, KEVIN C · 2008 to 2018
$1.6M
NIAMS NIH HHS 2K24 AR053120-06NIAMS NIH HHS 2R01 AR047328-06NIAMS NIH HHS K24 AR053120NIAMS NIH HHS R01 AR047328NIAMS NIH HHS R01 AR062066
6 · The paper itself

Abstract

purposeTo evaluate control group selection in nonrandomized studies published in the Journal of Hand Surgery American (JHS).

methodsWe reviewed all papers published in JHS in 2013 to identify studies that used nonrandomized control groups. Data collected included type of study design and control group characteristics. We then appraised studies to determine whether authors discussed confounding and selection bias and how they controlled for confounding.

resultsThirty-seven nonrandomized studies were published in JHS in 2013. The source of control was either the same institution as the study group, a different institution, a database, or not provided in the manuscript. Twenty-nine (78%) studies statistically compared key characteristics between control and study group. Confounding was controlled with matching, exclusion criteria, or regression analysis. Twenty-two (59%) papers explicitly discussed the threat of confounding and 18 (49%) identified sources of selection bias.

conclusionsIn our review of nonrandomized studies published in JHS, papers had well-defined controls that were similar to the study group, allowing for reasonable comparisons. However, we identified substantial confounding and bias that were not addressed as explicit limitations, which might lead the reader to overestimate the scientific validity of the data. CLINICAL RELEVANCE: Incorporating a brief discussion of control group selection in scientific manuscripts should help readers interpret the study more appropriately. Authors, reviewers, and editors should strive to address this component of clinical importance.

Indexed as

Control GroupsHumansNon-Randomized Controlled Trials as TopicPatient SelectionPublishingResearch DesignConfoundingcontrol grouphand surgerynonrandomized studiesselection bias

Identifiers

PMID25447000
PMCPMC4791587

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.