SynthesisWorld journal of surgery2015
Systematic review and meta-analysis of the open abdomen and temporary abdominal closure techniques in non-trauma patients.
Synthesis in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04986943 (Use of the ABTHERA ADVANCE™ Open Abdomen Dressing in Patients With Necrotizing Pancreatitis), which is not on this map. Cited by 108 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of the ABTHERA ADVANCE™ Open Abdomen Dressing in Patients With Necrotizing Pancreatitis
Who cites it
108 citing papers in PubMed, 8 syntheses or guidelines pooled it, 265 citations in OpenAlex.
- Contemporary management of the open abdomen: standards, challenges, and future directions.Langenbeck's archives of surgery · 2026Pooled it
- [Clinical disaster medicine: recommendations of the Surgical Working Group for Military and Emergency Surgery].Unfallchirurgie (Heidelberg, Germany) · 2025Guideline
- Vacuum-assisted closure or primary closure with relaparotomy on-demand in patients with secondary peritonitis: a systematic review and meta-analysis.World journal of emergency surgery : WJES · 2025Pooled it
- Negative pressure wound therapy for managing the open abdomen in non-trauma patients.The Cochrane database of systematic reviews · 2022Pooled it
- Oncologic feasibility for negative pressure wound therapy application in surgical wounds: A meta-analysis.International wound journal · 2022Pooled it
- Dynamic Fascial Closure With Vacuum-Assisted Wound Closure and Mesh-Mediated Fascial Traction (VAWCM) Treatment of the Open Abdomen-An Updated Systematic Review.Frontiers in surgery · 2020Pooled it
- Prophylactic Negative Pressure Wound Therapy in Closed Abdominal Incisions: A Meta-analysis of Randomised Controlled Trials.World journal of surgery · 2019Pooled it
- EHS clinical guidelines on the management of the abdominal wall in the context of the open or burst abdomen.Hernia : the journal of hernias and abdominal wall surgery · 2018Guideline
- Comparison of Maylard and Cherney incisions' outcomes in hysterectomy surgery for benign indications: a double-blind randomized controlled trial.European journal of medical research · 2025Trial
- The unrestricted global effort to complete the COOL trial.World journal of emergency surgery : WJES · 2023Trial
- Negative Pressure Wound Therapy vs Conventional Wound Treatment in Subcutaneous Abdominal Wound Healing Impairment: The SAWHI Randomized Clinical Trial.JAMA surgery · 2020Trial
- Article
- Skin-Only Closure Versus Bogota Bag: A Comparative Study of Complete Fascial Approximation Rates.Cureus · 2026Article
- Diagnosis and surgical management of septic peritonitis in small animals: A review.Veterinary surgery : VS · 2026Review
- Successful Re-Closure with Adjunctive Retention Sutures for Fascial Dehiscence after Mesh-Mediated Fascial Traction in Open Abdomen Management for Perforated Sigmoid Diverticulitis: A Case Report.Surgical case reports · 2026Article
- Late closure of the open abdomen in emergency abdomino-pelvic surgery: Advanced indications to negative pressure wound therapy?World journal of emergency surgery : WJES · 2025Article
- Article
- Article
- Early application of abdominal re-approximation anchor system for the management of the open abdomen.Scientific reports · 2025Article
- Modification of Negative Pressure Wound Therapy and Mesh-Mediated Fascial Traction for Open Abdomen Treatment.Cureus · 2025Article
48 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral challenging clinical situations in patients with peritonitis can result in an open abdomen (OA) and subsequent temporary abdominal closure (TAC). Indications and treatment choices differ among surgeons. The risk of fistula development and the possibility to achieve delayed fascial closure differ between techniques. The aim of this study was to review the literature on the OA and TAC in peritonitis patients, to analyze indications and to assess delayed fascial closure, enteroatmospheric fistula and mortality rate, overall and per TAC technique.
methodsElectronic databases were searched for studies describing the OA in patients of whom 50% or more had peritonitis of a non-traumatic origin.
resultsThe search identified 74 studies describing 78 patient series, comprising 4,358 patients of which 3,461 (79%) had peritonitis. The overall quality of the included studies was low and the indications for open abdominal management differed considerably. Negative pressure wound therapy (NPWT) was the most frequent described TAC technique (38 of 78 series). The highest weighted fascial closure rate was found in series describing NPWT with continuous mesh or suture mediated fascial traction (6 series, 463 patients: 73.1%, 95% confidence interval 63.3-81.0%) and dynamic retention sutures (5 series, 77 patients: 73.6%, 51.1-88.1%). Weighted rates of fistula varied from 5.7% after NPWT with fascial traction (2.2-14.1%), 14.6% (12.1-17.6%) for NPWT only, and 17.2% after mesh inlay (17.2-29.5%).
conclusionAlthough the best results in terms of achieving delayed fascial closure and risk of enteroatmospheric fistula were shown for NPWT with continuous fascial traction, the overall quality of the available evidence was poor, and uniform recommendations cannot be made.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.