ArticleJournal of insect physiology2015
Coordinated changes in JH biosynthesis and JH hemolymph titers in Aedes aegypti mosquitoes.
Article in Journal of insect physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 44 citations in OpenAlex.
- Juvenile hormone induces phosphorylation of insulin/insulin-like growth factor signaling proteins in previtellogenic Aedes aegypti mosquitoes.Insect science · 2025Article
- Membrane-localized MET engages PVR to mediate extranuclear juvenile hormone signaling inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Review
- Insulin-like peptides and ovary ecdysteroidogenic hormone differentially stimulate physiological processes regulating egg formation in the mosquito Aedes aegypti.Insect biochemistry and molecular biology · 2023Article
- Automated analysis of feeding behaviors of females of the mosquito Aedes aegypti using a modified flyPAD system.Scientific reports · 2023Article
- Sugar restriction and blood ingestion shape divergent immune defense trajectories in the mosquito Aedes aegypti.Scientific reports · 2023Article
- miR-309a is a regulator of ovarian development in the oriental fruit fly Bactrocera dorsalis.PLoS genetics · 2022Article
- Identification and Evolution Analysis of the Complete Methyl Farnesoate Biosynthesis and Related Pathway Genes in the Mud Crab,International journal of molecular sciences · 2022Article
- A transcriptomic atlas ofeLife · 2022Article
- Juvenile hormone-induced histone deacetylase 3 suppresses apoptosis to maintain larval midgut in the yellow fever mosquito.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Aedes aegypti post-emergence transcriptome: Unveiling the molecular basis for the hematophagic and gonotrophic capacitation.PLoS neglected tropical diseases · 2021Article
- A mosquito juvenile hormone binding protein (mJHBP) regulates the activation of innate immune defenses and hemocyte development.PLoS pathogens · 2020Article
- Blood feeding activates the vitellogenic stage of oogenesis in the mosquito Aedes aegypti through inhibition of glycogen synthase kinase 3 by the insulin and TOR pathways.Developmental biology · 2019Article
- Juvenile hormone controls ovarian development in female Anopheles albimanus mosquitoes.Scientific reports · 2019Article
- Natural Product Discovery by Direct Analysis in Real Time Mass Spectrometry.Mass spectrometry (Tokyo, Japan) · 2019Article
- Juvenile hormone-regulated alternative splicing of theProceedings of the National Academy of Sciences of the United States of America · 2018Article
- JH biosynthesis and hemolymph titers in adult male Aedes aegypti mosquitoes.Insect biochemistry and molecular biology · 2018Article
- A mosquito hemolymph odorant-binding protein family member specifically binds juvenile hormone.The Journal of biological chemistry · 2017Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Juvenile hormone III (JH) is synthesized by the corpora allata (CA) and plays a key role in mosquito development and reproduction. A decrease in JH titer during the last instar larvae allows pupation and metamorphosis to proceed. As the anti-metamorphic role of JH comes to an end, the CA of the late pupa once again synthesizes JH, which plays an essential role in orchestrating reproductive maturation. In spite of the importance of Aedes aegypti as a vector, a detailed study of the changes of JH hemolymph titers during the gonotrophic cycle has never been performed. In the present studies, using a high performance liquid chromatography coupled to a fluorescent detector (HPLC-FD) method, we measured changes in JH levels in the hemolymph of female mosquitoes during the pupal and adult stages. Our results revealed tightly concomitant changes in JH biosynthesis and JH hemolymph titers during the gonotrophic cycle of female mosquito. Feeding high sugar diets resulted in an increase of JH titers, and mating also modified JH titers in hemolymph. In addition these studies confirmed that JH titer in mosquitoes is fundamentally determined by the rate of biosynthesis in the CA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.