Evidence map›Paper›PMID 25445356›Full record

ArticleNeuroscience letters2015

Direction of magnetoencephalography sources associated with feedback and feedforward contributions in a visual object recognition task.

Seppo P Ahlfors, Stephanie R Jones, Jyrki Ahveninen, Matti S Hämäläinen, John W Belliveau, Moshe Bar

Abstract read
In one paragraph

Article in Neuroscience letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Neuronal Modeling of Cross-Sensory Visual Evoked Magnetoencephalography Responses in the Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Overview of MEG.Organizational research methods · 2019
    Article
  11. Article
  12. Frontal Brain Asymmetry and Willingness to Pay.Frontiers in neuroscience · 2018
    Article
  13. Article
  14. Time-varying effective connectivity during visual object naming as a function of semantic demands.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seppo P AhlforsAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02135, USA. Electronic address: seppo@nmr.mgh.harvard.edu.
Stephanie R JonesAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA; Brown University, Providence, RI, USA.
Jyrki AhveninenAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA.
Matti S HämäläinenAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02135, USA.
John W BelliveauAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA; Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02135, USA.
Moshe BarAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA; Gonda Multidisciplinary Brain Research Center, Bar-Ilan University, Ramat-Gan 52900, Israel.

Funding

Project 4P41EB015896 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ROSEN, BRUCE R · 2012 to 2018
$9.8M
SPATIOTEMPORAL IMAGING OF HUMAN VISUAL SYSTEM PROCESSINGR01NS037462 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI · 1998 to 2013
$6.5M
Inferring Cortical Feed-Forward and Feedback Processes with Human NeuroimagingR01NS057500 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI · 2007 to 2009
$1.3M
Prefrontal -> Top Down Contribution to Object RecognitionR01EY019477 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI BAR, MOSHE · 2009 to 2010
$1.2M
Spatiotemporal imaging of human visual system processingR56NS037462 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI · 2015 to 2015
$550k
Inferring Cortical Feed-Forward and Feedback Processes with Human NeuroimagingR56NS057500 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AHLFORS, SEPPO PENTTI · 2010 to 2010
$500k
Elekta Neuromag Electronics UpgradeS10RR031599 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI HAMALAINEN, MATTI · 2011 to 2011
$350k
NCRR NIH HHS S10 RR031599NEI NIH HHS EY019477NEI NIH HHS R01 EY019477NIBIB NIH HHS P41 EB015896NIBIB NIH HHS P41EB015896NINDS NIH HHS NS37462NINDS NIH HHS NS57500NINDS NIH HHS R01 NS037462NINDS NIH HHS R01 NS057500NINDS NIH HHS R56 NS037462NINDS NIH HHS R56 NS057500
6 · The paper itself

Abstract

Identifying inter-area communication in terms of the hierarchical organization of functional brain areas is of considerable interest in human neuroimaging. Previous studies have suggested that the direction of magneto- and electroencephalography (MEG, EEG) source currents depend on the layer-specific input patterns into a cortical area. We examined the direction in MEG source currents in a visual object recognition experiment in which there were specific expectations of activation in the fusiform region being driven by either feedforward or feedback inputs. The source for the early non-specific visual evoked response, presumably corresponding to feedforward driven activity, pointed outward, i.e., away from the white matter. In contrast, the source for the later, object-recognition related signals, expected to be driven by feedback inputs, pointed inward, toward the white matter. Associating specific features of the MEG/EEG source waveforms to feedforward and feedback inputs could provide unique information about the activation patterns within hierarchically organized cortical areas.

Indexed as

Feedback, SensoryRecognition, PsychologyVisual PerceptionAdultBrain MappingCerebral CortexElectroencephalographyFemaleHumansMagnetoencephalographyMaleTemporal LobeBottom–upCerebral cortexCurrent dipoleMagnetoencephalographyTop–down

Identifiers

PMID25445356
PMCPMC4273496

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.