Evidence map›Paper›PMID 25445055›Full record

ArticleJournal of neuroscience methods2015

The absence of task-related increases in BOLD signal does not equate to absence of task-related brain activation.

Jiansong Xu, Vince D Calhoun, Marc N Potenza

Abstract read
In one paragraph

Article in Journal of neuroscience methods, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Cognition emerges from phase dynamics of intrinsic coordination.bioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jiansong XuDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States. Electronic address: Jiansong.xu@yale.edu.
Vince D CalhounDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States; The Mind Research Network, Albuquerque, NM 87131, United States; Department of ECE, The University of New Mexico, Albuquerque, NM 87131, United States.
Marc N PotenzaDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT 06510, United States; Child Study Center, Yale University School of Medicine, New Haven, CT 06510, United States; Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, United States.

Funding

TSF to enhance treatment of cocaine dependenceP50DA009241 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M. · 1994 to 2018
$40.5M
Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI ABBOTT, CHRISTOPHER C · 2012 to 2017
$14.3M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2010 to 2013
$3.6M
Neural mechanisms of CBT in cocaine dependence (Gender Differences Supplement)R01DA035058 · NIDA · YALE UNIVERSITY · PI CARROLL, KATHLEEN M., POTENZA, MARC N · 2013 to 2016
$2.3M
fMRI of CBT and CM for Cocaine DependenceR01DA020908 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2005 to 2009
$1.7M
FMRI & DTI Study on Neural Predictor of Treatment Outcome of Cocaine DependenceK01DA027750 · NIDA · YALE UNIVERSITY · PI XU, JIANSONG · 2010 to 2014
$881k
Cigarette Smoking and the Efficiency of the Frontoparietal Attentional NetworkR03DA022364 · NIDA · YALE UNIVERSITY · PI XU, JIANSONG · 2006 to 2006
$220k
NIDA NIH HHS K01 DA027750NIDA NIH HHS P20 DA027844NIDA NIH HHS P50 DA009241NIDA NIH HHS P50 DA09241NIDA NIH HHS R01 DA020908NIDA NIH HHS R01 DA035058NIDA NIH HHS R03 DA022364NIGMS NIH HHS P20 GM103472NIGMS NIH HHS P20GM103472
6 · The paper itself

Abstract

Most fMRI studies employ general-linear-model-based analyses (GLM-BA) of BOLD signal changes to identify regions that are active (or not) during specific cognitive processes. However, alternate analytic approaches (like independent component analysis) may identify more complex patterns of activation, including in regions not implicated in GLM-BA of the same data. In our opinion, fMRI findings revealed by a GLM-BA cannot exclude any brain regions from contributing to specific cognitive processes.

Indexed as

BrainBrain MappingCerebrovascular CirculationHumansImage Processing, Computer-AssistedLinear ModelsMagnetic Resonance ImagingMental ProcessesModels, NeurologicalNeuronsNeuropsychological TestsOxygenOxygenBalanced excitation and inhibitionFunctional heterogeneityGeneral linear modelSpatial independent component analysis

Identifiers

PMID25445055
PMCPMC4470484

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.