Evidence map›Paper›PMID 25443885›Full record

ReviewLeukemia research2015

Chronic mast cell leukemia: a novel leukemia-variant with distinct morphological and clinical features.

Peter Valent, Karl Sotlar, Wolfgang R Sperr, Andreas Reiter, Michel Arock, Hans-Peter Horny

Abstract readComparative StudyReview
In one paragraph

Review in Leukemia research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 95 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Peter ValentDepartment of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria. Electronic address: peter.valent@meduniwien.ac.at.
Karl SotlarInstitute of Pathology, Ludwig-Maximilians University, Munich, Germany.
Wolfgang R SperrDepartment of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Vienna, Austria.
Andreas ReiterIII. Medizinische Klinik, Universitäts-Medizin Mannheim, Universität Heidelberg, Mannheim, Germany.
Michel ArockLBPA CNRS UMR8113, Ecole Normale Supérieure de Cachan, Cachan, France.
Hans-Peter HornyInstitute of Pathology, Ludwig-Maximilians University, Munich, Germany.
Ludwig-Maximilians-Universität München · DEMedical University of Vienna · ATÉcole Normale Supérieure Paris-Saclay · FRHeidelberg University · DE

Funding

Austrian Science Fund FWF F 4704
6 · The paper itself

Abstract

Mast cell leukemia (MCL) is a rare form of systemic mastocytosis characterized by leukemic expansion of mostly immature mast cells, organ damage, drug-resistance, and a poor prognosis. Even when treated with chemotherapy, most patients have a life-expectancy of less than one year. However, there are rare patients with MCL in whom the condition is less aggressive and does not cause organ damage within a short time. In these patients, mast cells exhibit a more mature morphology when compared to acute MCL. A recently proposed classification suggests that these cases are referred to as chronic MCL. In the present article, we discuss clinical, histopathological and morphological aspects of acute and chronic MCL.

Indexed as

Drug Resistance, NeoplasmLeukemia, Mast-CellAcute DiseaseChronic DiseaseHumansChronic mast cell leukemiaKIT mutationMast cellsMastocytosis

Identifiers

PMID25443885
PMCPMC4896385
OpenAlexW2073689154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.