Evidence map›Paper›PMID 25443601›Full record

Trial reportIndian heart journal

Yoga based cardiac rehabilitation after coronary artery bypass surgery: one-year results on LVEF, lipid profile and psychological states--a randomized controlled study.

Nagarathna Raghuram, Venkateshwara Rao Parachuri, M V Swarnagowri, Suresh Babu, Ritu Chaku, Ravi Kulkarni, Bhagavan Bhuyan, Hemant Bhargav, Hongasandra Ramarao Nagendra

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04674865 (Effects of Anulom-Vilom Pranayama/ Alternate Nostril Breathing on Cardiorespiratory Functions in Phase 1 Post CABG Patients), which is not on this map. Cited by 26 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 10 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04674865 nacompletednot on this map

Effects of Anulom-Vilom Pranayama/ Alternate Nostril Breathing on Cardiorespiratory Functions in Phase 1 Post CABG Patients

TypeinterventionalSponsorRiphah International UniversityRan2020 to 2021Enrolled22ConditionsPost-cardiac SurgeryArmsStandardized Physical therapy protocol, Alternate nostrils breathing
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 10 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Pooled it
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  6. Exercise-based cardiac rehabilitation for coronary heart disease.The Cochrane database of systematic reviews · 2021
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  13. Significance of Yoga for the Management of Dyslipidemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
    Review
  14. Cardiac Rehabilitation After Open Heart Surgery: A Narrative Systematic Review.Journal of cardiovascular development and disease · 2024
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Nagarathna RaghuramDean, Division of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India. Electronic address: rnagaratna@gmail.com.
Venkateshwara Rao ParachuriDepartment of Cardiology, Narayana Hrudayalaya Institute of Cardiac Sciences, No. 258/A, Bommasandra Industrial Area, Hosur Road, Anekal Taluk, Karnataka, India.
M V SwarnagowriDivision of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India.
Suresh BabuDivision of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India; Department of Cardiology, Narayana Hrudayalaya Institute of Cardiac Sciences, No. 258/A, Bommasandra Industrial Area, Hosur Road, Anekal Taluk, Karnataka, India.
Ritu ChakuDivision of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India.
Ravi KulkarniSymbiosis International University, Pune, India.
Bhagavan BhuyanDepartment of Cardiology, Narayana Hrudayalaya Institute of Cardiac Sciences, No. 258/A, Bommasandra Industrial Area, Hosur Road, Anekal Taluk, Karnataka, India.
Hemant BhargavDivision of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India.
Hongasandra Ramarao NagendraDivision of Yoga and Life Sciences, Swami Vivekananda Yoga Anusandhana Samsthana University, 19 Eknath Bhavan, Gavipuram Circle, Kempegowda Nagar, Bangalore, Karnataka, India.
Swami Vivekananda Yoga Anusandhana Samsthana · INNarayana Health · INSymbiosis International University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the long term effects of yoga based cardiac rehabilitation program with only physiotherapy based program as an add-on to conventional rehabilitation after coronary artery bypass grafting (CABG) on risk factors.

methodsIn this single blind prospective randomized parallel two armed active control study, 1026 patients posted for CABG at Narayana Hrudayalaya Institute of Cardiac Sciences, Bengaluru (India) were screened. Of these, 250 male participants (35-65 years) who satisfied the selection criteria and consented were randomized into two groups. Within and between group comparisons were done at three points of follow up (i.e. 6th week, 6th month, and 12th month) by using Wilcoxon's signed ranks test and Mann Whitney U test respectively.

resultsYoga group had significantly (p = 0.001, Mann Whitney) better improvement in LVEF than control group in those with abnormal baseline EF (<53%) after 1 year. There was a better reduction in BMI in the yoga group (p = 0.038, between groups) in those with high baseline BMI (≥23) after 12 months. Yoga group showed significant (p = 0.008, Wilcoxon's) reduction in blood glucose at one year in those with high baseline FBS ≥110 mg/dl. There was significantly better improvement in yoga than the control group in HDL (p = 0.003), LDL (p = 0.01) and VLDL (p = 0.03) in those with abnormal baseline values. There was significantly better improvement (p = 0.02, between groups) in positive affect in yoga group. Within Yoga group, there was significant decrease in perceived stress (p = 0.001), anxiety (p = 0.001), depression (p = 0.001), and negative affect (p = 0.03) while in the control group there was reduction (p = 0.003) only in scores on anxiety.

conclusionAddition of yoga based relaxation to conventional post-CABG cardiac rehabilitation helps in better management of risk factors in those with abnormal baseline values and may help in preventing recurrence.

Indexed as

YogaAdultAgedCoronary Artery BypassHumansLipidsMaleMiddle AgedProspective StudiesSingle-Blind MethodStroke VolumeTreatment OutcomeLipidsCardiac rehabilitationLVEFPhysiotherapyRisk factorsYoga

Identifiers

PMID25443601
PMCPMC4223225
OpenAlexW2144767072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.