There is no credible rational for deep brain stimulation in very early Parkinson's disease!

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. Patients' experiences of deep brain stimulation for Parkinson's disease: a qualitative systematic review and synthesis.BMJ open · 2016
   Pooled it
2. Deep brain stimulation surgical timing, outcomes, and prognostic factors in patients with Parkinson's disease: A Chinese retrospective multicenter cohort study.PLoS medicine · 2025
   Article
3. Anthropology of Deep Brain Stimulation; the 30th Anniversary of STN DBS in 2023.Movement disorders clinical practice · 2023
   Review
4. How Does Deep Brain Stimulation Change the Course of Parkinson's Disease?Movement disorders : official journal of the Movement Disorder Society · 2022
   Review
5. Deep brain stimulation in Parkinson's disease: state of the art and future perspectives.Arquivos de neuro-psiquiatria · 2022
   Review
6. DBS: a compelling example for ethical and legal reflection-a French perspective on ethical and legal concerns about DBS.Monash bioethics review · 2020
   Article
7. Patient's lived experience with DBS between medical research and care: some legal implications.Medicine, health care, and philosophy · 2019
   Article
8. BDNF provides many routes toward STN DBS-mediated disease modification.Movement disorders : official journal of the Movement Disorder Society · 2019
   Article
9. Neuroprotective Surgical Strategies in Parkinson's Disease: Role of Preclinical Data.International journal of molecular sciences · 2017
   Review
10. My 25 Stimulating Years with DBS in Parkinson's Disease.Journal of Parkinson's disease · 2017
    Article
11. Deep brain stimulation for Parkinson's disease prior to L-dopa treatment: A case report.Surgical neurology international · 2016
    Article
12. Deep Brain Stimulation: A Paradigm Shifting Approach to Treat Parkinson's Disease.Frontiers in neuroscience · 2016
    Review
13. Deep brain stimulation for movement disorders: update on recent discoveries and outlook on future developments.Journal of neurology · 2015
    Review

Corrections and comments

• Commented on by
  Deep brain stimulation in early stage Parkinson's disease.2015
• Commented on by
  Deep brain stimulation in early stage Parkinson's disease may reduce the relative risk of symptom worsening.2016
• Comment on
  Subthalamic nucleus deep brain stimulation in early stage Parkinson's disease.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as