Evidence map›Paper›PMID 25443078›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Older age does not limit postbariatric surgery cognitive benefits: a preliminary investigation.

Michael L Alosco, Ronald Cohen, Mary Beth Spitznagel, Gladys Strain, Michael Devlin, Ross D Crosby, James E Mitchell, John Gunstad

Abstract readMulticenter Study
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Michael L AloscoKent State University, Kent, Ohio.
Ronald CohenUniversity of Florida Institute on Aging, Gainesville, Florida.
Mary Beth SpitznagelKent State University, Kent, Ohio.
Gladys StrainWeill Cornell Medical College, New York, New York.
Michael DevlinColumbia University Medical Center, New York, New York.
Ross D CrosbyUniversity of North Dakota School of Medicine and Health Sciences and Neuropsychiatric Research Institute, Fargo, North Dakota.
James E MitchellUniversity of North Dakota School of Medicine and Health Sciences and Neuropsychiatric Research Institute, Fargo, North Dakota.
John GunstadKent State University, Kent, Ohio. Electronic address: jgunstad@kent.edu.
Kent State University · USColumbia University Irving Medical Center · USCornell University · USInstitute on Aging · USNeuropsychiatric Research Institute · USUniversity of North Dakota · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain FunctionR01DK099334 · NIDDK · UNIVERSITY OF FLORIDA · PI RONALD A COHEN, Eric Porges · 2014 to 2026
$4.6M
Cognitive Benefits of Cardiac Rehabilitation in Heart FailureR01HL089311 · NHLBI · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2008 to 2012
$2.6M
Cognitive Effects of Bariatric SurgeryR01DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2006 to 2009
$1.5M
Extended Effects of Bariatric Surgery on Cognitive FunctionR56DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2010 to 2010
$296k
NHLBI NIH HHS HL089311NHLBI NIH HHS R01 HL089311NIA NIH HHS P30 AG028740NIDDK NIH HHS DK075119NIDDK NIH HHS R01 DK075119NIDDK NIH HHS R01 DK099334NIDDK NIH HHS R56 DK075119
6 · The paper itself

Abstract

backgroundBariatric surgery is associated with cognitive benefits, but the nature of such gains may be variable across demographically and clinically diverse persons. Older adults achieve less weight loss and resolution of fewer medical co-morbidities after surgery compared to younger patients and are also at heightened risk for nutritional deficiencies. However, no study has examined the influence of age on cognitive improvements after bariatric surgery. The objective of this study was to determine the effects of age on cognitive function postbariatric surgery.

methodsA total of 95 participants enrolled in the Longitudinal Assessment for Bariatric Surgery completed a computerized cognitive test battery before bariatric surgery and at 12-weeks and 12-months postoperatively.

resultsBaseline cognitive impairments were common. Significant improvements were found in attention/executive function and memory abilities 12-weeks and 12-months after surgery. Age was not associated with baseline cognitive test performance. Separate multivariable regression analyses controlling for baseline attention/executive function and memory also showed that age was not a significant predictor of 12-week or 12-month performances in these domains (P>.05 for all).

conclusionThe present study provides preliminary evidence suggesting that older age does not preclude postbariatric surgery cognitive benefits. Prospective studies in more age diverse samples (i.e., up to 70 yr) are needed to determine whether bariatric surgery can reduce risk of age-related neurologic conditions like Alzheimer's disease and stroke.

Indexed as

AdultAgedAge FactorsAgingAnalysis of VarianceBariatric SurgeryBody Mass IndexCognitionExecutive FunctionFemaleFollow-Up StudiesHumansLaparoscopyLongitudinal StudiesMaleMemoryAgeBariatric surgeryCognitive functionObesityOlder adults

Identifiers

PMID25443078
PMCPMC4255023
OpenAlexW2003892041

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.