Trial reportOphthalmology2015
Five-year treatment outcomes in the Ahmed Baerveldt comparison study.
Trial report in Ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 137 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ahmed Versus Baerveldt Comparison Study
The AGS Second Aqueous Shunt Implant vs. Transscleral Cyclophotocoagulation Treatment Study
Who cites it
137 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Outcomes of Baerveldt implantation for pediatric glaucoma following surgery: a systematic review and meta-analysis.International ophthalmology · 2025Pooled it
- Ahmed and baerveldt in glaucoma surgery: what is the safest choice? - a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Pooled it
- A systematic review and network meta-analysis of surgical interventions for glaucoma following penetrating keratoplasty.Scientific reports · 2025Pooled it
- Aqueous shunts for glaucoma.The Cochrane database of systematic reviews · 2017Pooled it
- Comparison of the Ahmed glaucoma valve with the Baerveldt glaucoma implant: a meta-analysis.BMC ophthalmology · 2015Pooled it
- Ahmed glaucoma valve implant for refractory glaucoma in children: A systematic review and meta-analysis.Science progressPooled it
- Efficacy of Ahmed and Baerveldt glaucoma drainage device implantation in the pediatric population: A systematic review and meta-analysis.Survey of ophthalmologyPooled it
- Postoperative Complications in the Primary Tube Versus Trabeculectomy Study During 5 Years of Follow-up.Ophthalmology · 2022Trial
- Risk Factors for Failure of Tube Shunt Surgery: A Pooled Data Analysis.American journal of ophthalmology · 2022Trial
- Comparing the trabecular outflow by the response to topical pilocarpine in patients with and without glaucoma filtering surgery.Japanese journal of ophthalmology · 2020Trial
- A prospective randomized controlled study of Aurolab aqueous drainage implant versus Ahmed glaucoma valve in refractory glaucoma: A pilot study.Indian journal of ophthalmology · 2018Trial
- Postoperative Complications in the Ahmed Baerveldt Comparison Study During Five Years of Follow-up.American journal of ophthalmology · 2016Trial
- Endophthalmitis following glaucoma drainage device surgery.Eye (London, England) · 2026Article
- Corneal tomography and endothelial cell density after Paul glaucoma implant surgery.Acta ophthalmologica · 2026Article
- Comparative efficacy of glaucoma drainage device versus ab-interno trabeculotomy in vitrectomized eyes with secondary glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- First-in-human implantation of a self-adjustable glaucoma drainage device (eyeValve): safety and performance in blind eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Novel Non-Valved Glaucoma Drainage Device with Reduced Inner Lumen Diameter: 6-Month Safety and Efficacy Outcomes.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- The JFC Method: A Proof-of-Concept Report on the Surgical Technique and Initial Feasibility of a Novel Flanged-Cord Temporary Occlusion for Non-Valved Glaucoma Drainage Devices.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Article
- Safety and Efficacy of the Ahmed ClearPath versus Ahmed ClearPath Small Tube at Six Months: A Retrospective Comparative Cohort Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
77 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeTo compare the 5-year outcomes of the Ahmed FP7 Glaucoma Valve (AGV) (New World Medical, Cucamonga, CA) and the Baerveldt 101-350 Glaucoma Implant (BGI) (Abbott Medical Optics, Abbott Park, IL) for the treatment of refractory glaucoma.
designMulticenter, randomized, controlled clinical trial.
participantsA total of 276 patients, including 143 in the AGV group and 133 in the BGI group.
methodsPatients aged 18 to 85 years with previous intraocular surgery or refractory glaucoma and intraocular pressure (IOP) of ≥18 mmHg in whom glaucoma drainage implant (GDI) surgery was planned were randomized to implantation of an AGV or a BGI.
main outcome measuresSurgical failure, IOP, visual acuity (VA), use of glaucoma medications, and complications.
resultsAt 5 years, IOP (mean ± standard deviation [SD]) was 14.7±4.4 mmHg in the AGV group and 12.7±4.5 mmHg in the BGI group (P = 0.015). The number of glaucoma medications in use at 5 years (mean ± SD) was 2.2±1.4 in the AGV group and 1.8±1.5 in the BGI group (P = 0.28). The cumulative probability of failure during 5 years of follow-up was 44.7% in the AGV group and 39.4% in the BGI group (P = 0.65). The number of subjects failing because of inadequately controlled IOP or reoperation for glaucoma was 46 in the AGV group (80% of AGV failures) and 25 in the BGI group (53% of BGI failures; P = 0.003). Eleven eyes in the AGV group (20% of AGV failures) experienced persistent hypotony, explantation of implant, or loss of light perception compared with 22 eyes (47% of failures) in the BGI group. Change in logarithm of the minimum angle of resolution VA (mean ± SD) at 5 years was 0.42±0.99 in the AGV group and 0.43±0.84 in the BGI group (P = 0.97).
conclusionsSimilar rates of surgical success were observed with both implants at 5 years. The BGI produced greater IOP reduction and a lower rate of glaucoma reoperation than the AGV, but the BGI was associated with twice as many failures because of safety issues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.