Evidence map›Paper›PMID 25439360›Full record

ReviewThe journal of allergy and clinical immunology. In practice

Allergic bronchopulmonary aspergillosis.

Paul A Greenberger, Robert K Bush, Jeffrey G Demain, Amber Luong, Raymond G Slavin, Alan P Knutsen

Open access · greenAbstract readReview
In one paragraph

Review in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 2 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. High total serum IgE level at diagnosis was associated with a progressive decline in lung function in asthmatic patients with allergic bronchopulmonary mycosis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  4. Article
  5. Article
  6. Indoor and Outdoor Fungal Allergens and Impacts on Respiratory Allergic Disease.The journal of allergy and clinical immunology. In practice · 2025
    Review
  7. Review
  8. Treatment of allergic bronchopulmonary aspergillosis with biologics.Chinese medical journal pulmonary and critical care medicine · 2025
    Review
  9. Article
  10. Article
  11. Bronchial Asthma and COVID-19: Etiology, Pathological Triggers, and Therapeutic Considerations.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
    Review
  12. Amphotericin B in the Era of New Antifungals: Where Will It Stand?Journal of fungi (Basel, Switzerland) · 2024
    Review
  13. Risk factors for short-term prognosis of end-stage liver disease complicated by invasive pulmonary aspergillosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  14. Review
  15. Article
  16. Severe Fungal Asthma: A Role for Biologics and Inhaled Antifungals.Journal of fungi (Basel, Switzerland) · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. The Role of Comorbidities in Difficult-to-Control Asthma in Adults and Children.The journal of allergy and clinical immunology. In practice · 2022
    Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Paul A GreenbergerDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: p-greenberger@northwestern.edu.
Robert K BushDivision of Allergy-Immunology, Department of Medicine, University of Wisconsin, Madison, Wis.
Jeffrey G DemainAllergy, Asthma and Immunology Center of Alaska, University of Washington, Anchorage, Alaska.
Amber LuongOtolaryngology-Head and Neck Surgery, University of Texas Medical School at Houston, Houston, Texas.
Raymond G SlavinSection of Allergy-Immunology, Division of Infectious Diseases, Department of Internal Medicine, St Louis University, St Louis, Mo.
Alan P KnutsenDivision of Allergy-Immunology, Department of Pediatrics, St Louis University, St Louis, Mo.
Saint Louis University · USNorthwestern University · USUniversity of Alaska Anchorage · USUniversity of Wisconsin–Madison · US

Funding

Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
Center for Clinical and Translational Sciences (CCTS)KL2TR000370 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$4.3M
NCATS NIH HHS KL2 TR000370NCATS NIH HHS UL1 TR000371
6 · The paper itself

Abstract

There remains a lack of agreement on diagnostic criteria and approaches to treatment of patients with allergic bronchopulmonary aspergillosis (ABPA). The results of a survey of American Academy of Allergy, Asthma, & Immunology members regarding these 2 issues are presented and compared for concordance with published recommendations. The literature was reviewed for pertinent reports, and an electronic survey was conducted of American Academy of Allergy, Asthma, & Immunology members and fellows regarding diagnostic criteria, numbers of patients evaluated for ABPA, and treatment approaches. From 508 respondents to the survey sent to 5155 US physicians in the American Academy of Allergy, Asthma, & Immunology database of members and fellows, 245 health professionals (48%) had treated at least 1 patient with ABPA in the previous year. For the diagnosis of ABPA, there was a difference in the threshold concentration of total serum IgE because 44.9% used ≥417 kU/L, whereas 42.0% used ≥1000 kU/L. Analysis of these findings suggests that ABPA might be underdiagnosed. With regard to pharmacotherapy, oral steroids were recommended for 97.1% of patients and oral steroids plus inhaled corticosteroids plus antifungal agent were used with 41.2% of patients. The armamentarium for treatment of ABPA includes oral corticosteroids as the initial treatment with inhaled corticosteroids used for management of persistent asthma. Azoles remain adjunctive. Published experience with omalizumab has been limited.

Indexed as

Allergy and ImmunologyAdministration, InhalationAdministration, OralAdrenal Cortex HormonesAntifungal AgentsAspergillosis, Allergic BronchopulmonaryBiomarkersGenetic Predisposition to DiseaseGuideline AdherenceHealth Care SurveysHumansImmunoglobulin EPractice Guidelines as TopicPractice Patterns, Physicians'Predictive Value of TestsRisk FactorsAdrenal Cortex HormonesAntifungal AgentsBiomarkersImmunoglobulin EAllergicAspergillosisAsthmaAzoleBronchopulmonarIgEMycosis

Identifiers

PMID25439360
PMCPMC4306287
OpenAlexW4292096413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.