Evidence map›Paper›PMID 25439354›Full record

ReviewThe journal of allergy and clinical immunology. In practice

Infection-related asthma.

Jared I Darveaux, Robert F Lemanske

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Review
  10. Review
  11. Potential Therapeutic Value of the STING Inhibitors.Molecules (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Type 2 or Non-Type 2 Asthma Exacerbations? That Is the Question.American journal of respiratory and critical care medicine · 2022
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors.

Jared I DarveauxDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wis; Division of Allergy/Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Robert F LemanskeDivision of Allergy/Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wis; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis. Electronic address: rfl@medicine.wisc.edu.

Funding

Virus-Bacterial Interactions and Exacerba of AsthmaP01HL070831 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2002 to 2017
$31.3M
Investigating Effects of Viral Infection on Lung DevelopmentR01HL097134 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SUN, XIN · 2009 to 2013
$2.4M
NHLBI NIH HHS P01 HL070831NHLBI NIH HHS R01 HL097134PHS HHS U10 098090
6 · The paper itself

Abstract

The role of infection in asthma is varied in that it may exacerbate established asthma or contribute to the initial development of the clinical onset of asthma. Mounting evidence implicates both roles with particular viral pathogens, namely human rhinovirus and respiratory syncytial virus, among the most likely culprits in asthma inception. Once asthma is present, infection, particularly viral infection, is a common precipitant of asthma exacerbations. Bacterial infections and colonization also have been associated with exacerbation and recurrent wheeze, an effect that may be independent or a cofactor with viruses. Atypical bacterial infections such as Mycoplasma pneumoniae and Chlamydia pneumoniae and fungi in the case of allergic bronchopulmonary aspergillosis, also play a potential role in inducing and exacerbating this disease. In addition, certain individuals may have a genetic predisposition toward viral-induced wheezing and the development of asthma. This article will discuss host and environmental factors, common pathogens, clinical characteristic, and genetic influences associated with infection-related asthma.

Indexed as

AnimalsAsthmaBacterial InfectionsComorbidityGenetic MarkersGenetic Predisposition to DiseaseHumansLungPhenotypePrognosisRespiratory Tract InfectionsRisk FactorsVirus DiseasesGenetic MarkersAsthmaBiomarkersExacerbationInfectionRespiratory syncytial virusRhinovirus

Identifiers

PMID25439354
PMCPMC5516525

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.