Evidence map›Paper›PMID 25439273›Full record

ReviewClinics in laboratory medicine2014

Microbiome in human immunodeficiency virus infection.

January T Salas, Theresa L Chang

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in laboratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. The respiratory microbiome of HIV-infected individuals.Expert review of anti-infective therapy · 2016
    Review
  13. Review
  14. An assessment of US microbiome research.Nature microbiology · 2016
    Article
  15. The Gut Microbiota and Immune System Relationship in Human Graft-versus-Host Disease.Mediterranean journal of hematology and infectious diseases · 2016
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

January T SalasDepartment of Microbiology and Molecular Genetics, Public Health Research Institute, Rutgers-New Jersey Medical School, 225 Warren Street, Newark, NJ 07103, USA.
Theresa L ChangDepartment of Microbiology and Molecular Genetics, Public Health Research Institute, Rutgers-New Jersey Medical School, 225 Warren Street, Newark, NJ 07103, USA. Electronic address: changth@njms.rutgers.edu.
Rutgers, The State University of New Jersey · US

Funding

Modulation of innate immunity,microbiome and HIV transmission by Depo-ProveraR01AI110372 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHANG, THERESA L, YANG, LIYING · 2013 to 2017
$3.0M
NIAID NIH HHS R01 AI110372NIAID NIH HHS R01AI110372
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) primary infection occurs at mucosa tissues, suggesting an intricate interplay between the microbiome and HIV infection. Recent advanced technologies of high-throughput sequencing and bioinformatics allow researchers to explore nonculturable microbes, including bacteria, virus, and fungi, and their association with diseases. HIV/simian immunodeficiency virus infection is associated with microbiome shifts and immune activation that may affect the outcome of disease progression. In this review, the authors focus on microbiome in HIV infection at various mucosal compartments. Understanding the relationship between microbiome and HIV may offer insights into development of better strategies for HIV prevention and treatment.

Indexed as

MicrobiotaCervix UteriFemaleHIV InfectionsHumansLungMaleMouthPenisRectumVaginaHIV pathogenesisHIV transmissionImmune activationMicrobial translocationMicrobiome

Identifiers

PMID25439273
PMCPMC4254659
OpenAlexW2080402357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.