Evidence map›Paper›PMID 25439228›Full record

ArticleThe Journal of allergy and clinical immunology2014

Cost of near-roadway and regional air pollution-attributable childhood asthma in Los Angeles County.

Sylvia Brandt, Laura Perez, Nino Künzli, Fred Lurmann, John Wilson, Manuel Pastor, Rob McConnell

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Childhood Air Pollution Exposure Associated with Self-reported Bronchitic Symptoms in Adulthood.American journal of respiratory and critical care medicine · 2024
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  5. Incorporating the impact of roadside barrier effects on dispersion into AERMOD.Journal of the Air & Waste Management Association (1995) · 2024
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  9. Conditions Leading to Elevated PMInternational journal of environmental research and public health · 2019
    Article
  10. Article
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  12. Review
  13. Electronic Cigarette Use and Respiratory Symptoms in Adolescents.American journal of respiratory and critical care medicine · 2017
    Article
  14. Article
  15. The hidden economic burden of air pollution-related morbidity: evidence from the Aphekom project.The European journal of health economics : HEPAC : health economics in prevention and care · 2016
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Sylvia BrandtCenter for Public Policy and Administration and the Department of Resource Economics, University of Massachusetts Amherst, Amherst, Mass. Electronic address: sylvbrandt@gmail.com.
Laura PerezUniversity of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Nino KünzliUniversity of Basel, Basel, Switzerland; Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Fred LurmannSonoma Technology, Petaluma, Calif.
John WilsonSpatial Science Institute, University of Southern California, Los Angeles, Calif.
Manuel PastorProgram for Environmental and Regional Equity, University of Southern California, Los Angeles, Calif.
Rob McConnellDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, Calif.
University of Southern California · USSwiss Tropical and Public Health Institute · CHAmherst College · USSonoma Technology (United States) · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Urban Air Pollution and Children's Respiratory HealthP01ES011627 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES · 2002 to 2011
$30.2M
Urban Air Pollution &Persistent Early Life AsthmaP01ES009581 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILLILAND, FRANK D. · 1999 to 2010
$6.8M
Air Pollution and Preclinical Atherosclerosis in Elementary-School ChildrenR01ES014447 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AVOL, EDWARD · 2006 to 2009
$3.5M
Childhood Asthma, Susceptibility and Biological Activity of Ambient ParticlesR01ES016535 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2008 to 2011
$2.0M
NIEHS NIH HHS 5R01ES014447NIEHS NIH HHS P01 ES009581NIEHS NIH HHS P01ES009581NIEHS NIH HHS P01 ES011627NIEHS NIH HHS P01ES011627NIEHS NIH HHS P30 ES007048NIEHS NIH HHS P30ES007048NIEHS NIH HHS R01 ES014447NIEHS NIH HHS R01 ES016535
6 · The paper itself

Abstract

backgroundEmerging evidence suggests that near-roadway air pollution (NRP) exposure causes childhood asthma. The associated costs are not well documented.

objectiveWe estimated the cost of childhood asthma attributable to residential NRP exposure and regional ozone (O3) and nitrogen dioxide (NO2) levels in Los Angeles County. We developed a novel approach to apportion the costs between these exposures under different pollution scenarios.

methodsWe integrated results from a study of willingness to pay to reduce the burden of asthma with results from studies of health care use and charges to estimate the costs of an asthma case and exacerbation. We applied those costs to the number of asthma cases and exacerbations caused by regional pollution in 2007 and to hypothetical scenarios of a 20% reduction in regional pollution in combination with a 20% reduction or increase in the proportion of the total population living within 75 m of a major roadway.

resultsCost of air pollution-related asthma in Los Angeles County in 2007 was $441 million for O3 and $202 million for NO2 in 2010 dollars. Cost of routine care (care in absence of exacerbation) accounted for 18% of the combined NRP and O3 cost and 39% of the combined NRP and NO2 cost; these costs were not recognized in previous analyses. NRP-attributable asthma accounted for 43% (O3) to 51% (NO2) of the total annual cost of exacerbations and routine care associated with pollution. Hypothetical scenarios showed that costs from increased NRP exposure might offset savings from reduced regional pollution.

conclusionsOur model disaggregates the costs of regional pollution and NRP exposure and illustrates how they might vary under alternative exposure scenarios. The cost of air pollution is a substantial burden on families and an economic loss for society.

Indexed as

AdolescentAir PollutantsAsthmaCaliforniaChildChild, PreschoolCosts and Cost AnalysisFemaleHumansMaleNitrogen DioxideOxidants, PhotochemicalOzoneVehicle EmissionsAir PollutantsNitrogen DioxideOxidants, PhotochemicalOzoneVehicle EmissionsAir pollutionasthmacost of illnessurban growthvehicle emissionswillingness to pay

Identifiers

PMID25439228
PMCPMC4257136
OpenAlexW2067104052

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.