Evidence map›Paper›PMID 25439074›Full record

ReviewBest practice & research. Clinical gastroenterology2014

Implementation of gastric cancer screening - the global experience.

Mārcis Leja, Weicheng You, M Constanza Camargo, Hiroshi Saito

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Best practice & research. Clinical gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04022109 recruitingnot on this mapstarted 2019, after this paper: background citation

Screening of Gastric Cancer Via Breath Volatile Organic Compounds by Hybrid Sensing Approach

TypeobservationalSponsorUniversity of LatviaRan2019 to 2026Enrolled5,000ConditionsGastric Cancer, Atrophic Gastritis, Gastric Dysplasia, H.Pylori InfectionArmsBreath sampling for VOC detection, Surgery material collection for VOC headspace analysis, Upper endoscopy, Microbiota testing
NCT06316882 completednot on this mapstarted 2023, after this paper: background citation

ROGCAS - Retrospective Observational Gastric Cancer Study

TypeobservationalSponsorUnidade Local De Saúde Do Norte AlentejanoRan2023 to 2025Enrolled349ConditionsGastric Cancer, Gastric (Stomach) Cancer, Atrophic Gastritis, Intestinal Metaplasia of Gastric MucosaArmsScreening endoscopy
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Open versus minimally invasive total gastrectomy after neoadjuvant chemotherapy: results of a European randomized trial.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Trial
  3. European Cancer Prevention Organization on cancer screening: an expert panel position paper.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
    Article
  4. RSC advances · 2025
    Review
  5. Review
  6. Racial disparities of gastric cancer in the USA: an overview of epidemiology, global screening guidelines, and targeted screening in a heterogeneous population.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024
    Review
  7. Article
  8. Review
  9. Performance evaluation of four prediction models for risk stratification in gastric cancer screening among a high-risk population in China.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Article
  10. Downregulating circRNA_0044516 Inhibits Cell Proliferation in Gastric Cancer Through miR-149/Wnt1/β-catenin Pathway.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Recent advances in gastric cancer early diagnosis.World journal of gastroenterology · 2019
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Mārcis LejaFaculty of Medicine, University of Latvia, 6 Linezera iela, LV1006 Riga, Latvia. Electronic address: cei@latnet.lv.
Weicheng YouKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing 100142, PR China. Electronic address: weichengyou@yahoo.com.
M Constanza CamargoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA. Electronic address: camargomc@mail.nih.gov.
Hiroshi SaitoCancer Screening Assessment & Management Division, Research Center for Cancer Prevention & Detection, National Cancer Center, Tokyo 104-0045, Japan. Electronic address: hrsaito@ncc.go.jp.
Division of Cancer Epidemiology and GeneticsPeking University · CNUniversity of Latvia · LV

Funding

Molecular mechanisms of infection-related cancerZIACP010212 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ENGELS, ERIC A · 2010 to 2025
$4.6M
Intramural NIH HHS ZIA CP010212
6 · The paper itself

Abstract

Gastric cancer (GC) is still an important global healthcare problem, and in absolute figures it is going to remain at the present level in foreseeable future. In general, survival of patients with GC is poor mainly due to advanced-stage diagnosis. Early-stage GC can be cured by endoscopic resection or less invasive surgical treatment. Unfortunately, there is no appropriate screening strategy available for global application. This article provides a description of established national and regional GC screening programs and the screening modalities used. This review also summarizes current approaches to develop cancer-screening biomarkers. Although candidates with initial promising results have been suggested, moving discovery into clinical practice is still a major challenge. Well-designed biomarker studies, with systematic validation steps, are needed to decrease the burden of this fatal disease.

Indexed as

Early Detection of CancerBiomarkers, TumorGlobal HealthHumansStomach NeoplasmsBiomarkers, TumorBiomarkersGastric cancerHelicobacter pyloriPrecancerous lesionsScreening

Identifiers

PMID25439074
PMCPMC5847270
OpenAlexW2055665653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.