ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2015
Contributions of motoneuron hyperexcitability to clinical spasticity in hemispheric stroke survivors.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- The Benefits of Advanced Botulinum Neurotoxin Injection Training from a Spasticity Management Fellowship.Toxins · 2026Article
- Ischemic injury to primary motor and premotor cortices is linked to hyperreflexia in mice.Neurobiology of disease · 2026Article
- Excitation-inhibition imbalance in the motor control network: a key factor in post-stroke spasticity.Frontiers in human neuroscience · 2025Review
- Corticospinal tract: a new hope for the treatment of post-stroke spasticity.Acta neurologica Belgica · 2024Review
- Assessment of Passive Upper Limb Stiffness and Its Function in Post-Stroke Individuals Wearing an Inertial Sensor during the Pendulum Test.Sensors (Basel, Switzerland) · 2023Article
- Modification of Spastic Stretch Reflexes at the Elbow by Flexion Synergy Expression in Individuals With Chronic Hemiparetic Stroke.Archives of physical medicine and rehabilitation · 2018Article
- Altered Neuromodulatory Drive May Contribute to Exaggerated Tonic Vibration Reflexes in Chronic Hemiparetic Stroke.Frontiers in human neuroscience · 2018Article
- Bilateral changes in afterhyperpolarization duration of spinal motoneurones in post-stroke patients.PloS one · 2018Article
- Sound-Evoked Biceps Myogenic Potentials Reflect Asymmetric Vestibular Drive to Spastic Muscles in Chronic Hemiparetic Stroke Survivors.Frontiers in human neuroscience · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveMuscle spasticity is one of the major impairments that limits recovery in hemispheric stroke survivors. One potential contributing mechanism is hyperexcitability of motoneurons. Previously, the response latency of the surface electromyogram (EMG) record evoked by joint rotation has been used to characterize motoneuron excitability. Given the limitations of this method, the objective of the current study was to reexamine the excitability of motoneurons in chronic stroke survivors by estimating reflex latency using single motor unit discharge.
methodsWe quantified the excitability of spastic motoneurons using the response latency of a single motor unit discharge elicited by a position controlled tap on the biceps brachii tendon. We applied tendon taps of different amplitudes on the biceps tendons of both arms of the stroke survivors. Unitary reflex responses were recorded using intramuscular EMG recordings.
resultsOur results showed that the latency of unitary discharge was systematically shorter in the spastic muscle compared with the contralateral muscle, and this effect was consistent across multiple tap amplitudes.
conclusionsThis method allowed us to quantify latencies more accurately, potentially enabling a more rigorous analysis of contributing mechanisms. SIGNIFICANCE: The findings provide evidence supporting a contribution of hyperexcitable motoneurons to muscle spasticity.
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