Evidence map›Paper›PMID 25438039›Full record

ArticlePloS one2014

Treatment adherence and health outcomes in MSM with HIV/AIDS: patients enrolled in "one-stop" and standard care clinics in Wuhan China.

Wang Zhou, Min Zhao, Xia Wang, Robert F Schilling, Sheng Zhou, Hong-Yan Qiu, Nian-Hua Xie, Man-Qing Liu, Han-Sheng Dong, Zhong-Zhao Yao and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Wang ZhouWuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
Min ZhaoWuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
Xia WangWuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
Robert F SchillingDepartment of Social Welfare, Luskin School of Public Affairs, University of California Los Angeles, Los Angeles, California, United States of America.
Sheng ZhouDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.
Hong-Yan QiuWuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
Nian-Hua XieWuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
Man-Qing LiuWuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
Han-Sheng DongWuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
Zhong-Zhao YaoWuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
Thomas CaiAIDS Care of China, Nanning, Guangxi, China.
Wuhan Center for Disease Control and Prevention · CNCenters for Disease Control and Prevention · USJohns Hopkins University · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConducted in Wuhan China, this study examined follow-up and health markers in HIV patients receiving care in two treatment settings. Participants, all men who have sex with men, were followed for 18-24 months.

methodPatients in a "one-stop" service (ACC; N = 89) vs those in standard care clinics (CDC; N = 243) were compared on HIV treatment and retention in care outcomes.

resultsAmong patients with CD4 cell count ≦350 cells/µL, the proportion receiving cART did not differ across clinic groups. The ACC was favored across five other indicators: proportion receiving tests for CD4 cell count at the six-month interval (98.2% vs. 79.4%, 95% CI 13.3-24.3, p = 0.000), proportion with HIV suppression for patients receiving cART for 6 months (86.5% vs. 57.1%, 95% CI 14.1-44.7, p = 0.000), proportion with CD4 cell recovery for patients receiving cART for 12 months (55.8% vs. 22.2%, 95% CI 18.5-48.6, p = 0.000), median time from HIV confirmation to first test for CD4 cell count (7 days, 95% CI 4-8 vs. 10 days, 95% CI 9-12, log-rank p = 0.000) and median time from first CD4 cell count ≦350 cells/µL to cART initiation (26 days, 95% CI 16-37 vs. 41.5 days, 95% CI 35-46, log-rank p = 0.031). Clinic groups did not differ on any biomedical indicator at baseline, and no baseline biomedical or demographic variables remained significant in the multivariate analysis. Nonetheless, post-hoc analyses suggest the possibility of self-selection bias.

conclusionsStudy findings lend preliminary support to a one-stop patient-centered care model that may be useful across various HIV care settings.

Indexed as

Homosexuality, MaleAcquired Immunodeficiency SyndromeAdolescentAdultAgedAged, 80 and overAnti-HIV AgentsChinaHIV InfectionsHumansMaleMiddle AgedPatient-Centered CarePatient ComplianceTreatment OutcomeYoung AdultAnti-HIV Agents

Identifiers

PMID25438039
PMCPMC4249979
OpenAlexW2069154176

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.