Evidence map›Paper›PMID 25438013›Full record

ArticlePathogens (Basel, Switzerland)2014

Mycobacterium avium Subspecies paratuberculosis: Human Exposure through Environmental and Domestic Aerosols.

Glenn Rhodes, Hollian Richardson, John Hermon-Taylor, Andrew Weightman, Andrew Higham, Roger Pickup

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  6. Evolutionary genomic and bacteria GWAS analysis ofApplied and environmental microbiology · 2021
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  7. Presence ofMicroorganisms · 2019
    Article
  8. Article
  9. Open veterinary journal · 2018
    Review
  10. Article
  11. Review
  12. Article
  13. Mycobacterium paratuberculosis as a cause of Crohn's disease.Expert review of gastroenterology & hepatology · 2015
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Glenn RhodesCentre for Ecology and Hydrology, Lake Ecosystems Group, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP, UK. Glenn@ceh.ac.uk.
Hollian RichardsonFaculty of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster LA1 4YQ, UK. h.richardson2@lancaster.ac.uk.
John Hermon-TaylorDivision of Diabetes and Nutritional Sciences, Franklin-Wilkins Building, King's College London, 150 Stamford Street, London SE1 9NH, UK. j.hermon@kcl.ac.uk.
Andrew WeightmanCardiff School of Biosciences, Main Building, Museum Avenue, Cardiff CF10 3AT, UK. a.weightman@cardiff.ac.uk.
Andrew HighamRoyal Lancaster Infirmary, Ashton Road, Lancaster, Lancashire LA1 4RP, UK. Andrew.Higham@mbht.nhs.uk.
Roger PickupFaculty of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, Lancaster LA1 4YQ, UK. r.pickup@lancaster.ac.uk.
Lancaster University · GBCardiff University · GBKing's College London · GBRoyal Lancaster Infirmary · GBUK Centre for Ecology & Hydrology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacterium avium subspecies paratuberculosis (Map) causes Johne's disease in animals and is significantly associated with Crohn's disease (CD) in humans. Our previous studies have shown Map to be present in U.K. rivers due to land deposition from chronic livestock infection and runoff driven by rainfall. The epidemiology of CD in Cardiff showed a significant association with the River Taff, in which Map can be detected on a regular basis. We have previously hypothesized that aerosols from the river might influence the epidemiology of CD. In this preliminary study, we detected Map by quantitative PCR in one of five aerosol samples collected above the River Taff. In addition, we examined domestic showers from different regions in the U.K. and detected Map in three out of 30 independent samples. In detecting Map in river aerosols and those from domestic showers, this is the first study to provide evidence that aerosols are an exposure route for Map to humans and may play a role in the epidemiology of CD.

Identifiers

PMID25438013
PMCPMC4243430
OpenAlexW1976186856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.