Evidence map›Paper›PMID 25437798›Full record

ReviewPathogens (Basel, Switzerland)2014

Integrons in the intestinal microbiota as reservoirs for transmission of antibiotic resistance genes.

Anuradha Ravi, Ekaterina Avershina, Jane Ludvigsen, Trine M L'Abée-Lund, Knut Rudi

Open access · goldAbstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Resistance integrons; A Mini review.Caspian journal of internal medicine · 2019
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Three Bacterial Lines of Defense against Antimicrobial Agents.International journal of molecular sciences · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anuradha RaviNorwegian University of Life Sciences, Chemistry, Biotechnology and Food science department (IKBM), Campus Ås, Ås 1432, Norway. anuradha.ravi@nmbu.no.
Ekaterina AvershinaNorwegian University of Life Sciences, Chemistry, Biotechnology and Food science department (IKBM), Campus Ås, Ås 1432, Norway. ekaterina.avershina@nmbu.no.
Jane LudvigsenNorwegian University of Life Sciences, Chemistry, Biotechnology and Food science department (IKBM), Campus Ås, Ås 1432, Norway. jane.ludvigsen@nmbu.no.
Trine M L'Abée-LundNorwegian University of Life Sciences, Department of Food Safety and Infection Biology, Campus Adamstuen, Oslo 0454, Norway. trine.labee-lund@nmbu.no.
Knut RudiNorwegian University of Life Sciences, Chemistry, Biotechnology and Food science department (IKBM), Campus Ås, Ås 1432, Norway. knut.rudi@nmbu.no.
Norwegian University of Life Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human intestinal microbiota plays a major beneficial role in immune development and resistance to pathogens. The use of antibiotics, however, can cause the spread of antibiotic resistance genes within the resident intestinal microbiota. Important vectors for this are integrons. This review therefore focuses on the integrons in non-pathogenic bacteria as a potential source for the development and persistence of multidrug resistance. Integrons are a group of genetic elements which are assembly platforms that can capture specific gene cassettes and express them. Integrons in pathogenic bacteria have been extensively investigated, while integrons in the intestinal microbiota have not yet gained much attention. Knowledge of the integrons residing in the microbiota, however, can potentially aid in controlling the spread of antibiotic resistance genes to pathogens.

Identifiers

PMID25437798
PMCPMC4243444
OpenAlexW2077130254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.