ReviewPathogens (Basel, Switzerland)2013
The metabolic and ecological interactions of oxalate-degrading bacteria in the Mammalian gut.
Review in Pathogens (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- The gut microbiota profile of adults with kidney disease and kidney stones: a systematic review of the literature.BMC nephrology · 2020Pooled it
- Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Review
- Role of Microbial Toxins in Neurodegenerative Diseases: Insights and Future Perspectives.Biomolecules · 2026Review
- Characterization of Gut Bacteria inInsects · 2026Article
- Role of gut microbiota dysbiosis in podophyllotoxin-induced neurotoxicity in zebrafish: linking purine metabolism to synaptic dysfunction.BMC microbiology · 2026Article
- Predicting probiotic success: lessons from Oxalobacter and oxalate metabolism.NPJ biofilms and microbiomes · 2026Review
- Effects of salinity and broad-range antibiotics on oxalate production, transport, and degradation in Poecilia latipinna.PloS one · 2026Article
- Analysis of 33,616 urinary stone cases: novel findings on renal transplantation impact, comorbidity profiles, and composition patterns.Frontiers in immunology · 2026Observational
- Adherence to the Dietary Index for Gut Microbiota and reduced risk of nephrolithiasis: a case-control study of Chinese adults.Frontiers in nutrition · 2026Article
- Article
- Body mass index mediates the association between the dietary index for gut microbiota and kidney stones: a cross-sectional study.BMC public health · 2025Article
- Complex system modeling reveals oxalate homeostasis is driven by diverse oxalate-degrading bacteria.eLife · 2025Article
- The gut-kidney axis in urolithiasis: roles of gut microbiota, metabolites, and therapeutic implications.Frontiers in microbiology · 2025Review
- National analysis of the dietary index for gut microbiota and kidney stones: evidence from NHANES (2007-2018).Frontiers in nutrition · 2025Article
- Secondary products and molecular mechanism of calcium oxalate degradation by the strain Azospirillum sp. OX-1.Scientific reports · 2024Article
- Unraveling the role of gut microbiota by fecal microbiota transplantation in rat model of kidney stone disease.Scientific reports · 2024Article
- Gut and Urinary Microbiota in Cats with Kidney Stones.Microorganisms · 2024Article
- Plant-Based Fermented Beverages: Nutritional Composition, Sensory Properties, and Health Benefits.Foods (Basel, Switzerland) · 2024Review
- Deficient butyrate metabolism in the intestinal microbiome is a potential risk factor for recurrent kidney stone disease.Urolithiasis · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxalate-degrading bacteria comprise a functional group of microorganisms, commonly found in the gastrointestinal tract of mammals. Oxalate is a plant secondary compound (PSC) widely produced by all major taxa of plants and as a terminal metabolite by the mammalian liver. As a toxin, oxalate can have a significant impact on the health of mammals, including humans. Mammals do not have the enzymes required to metabolize oxalate and rely on their gut microbiota for this function. Thus, significant metabolic interactions between the mammalian host and a complex gut microbiota maintain the balance of oxalate in the body. Over a dozen species of gut bacteria are now known to degrade oxalate. This review focuses on the host-microbe and microbe-microbe interactions that regulate the degradation of oxalate by the gut microbiota. We discuss the pathways of oxalate throughout the body and the mammalian gut as a series of differentiated ecosystems that facilitate oxalate degradation. We also explore the mechanisms and functions of microbial oxalate degradation along with the implications for the ecological and evolutionary interactions within the microbiota and for mammalian hosts. Throughout, we consider questions that remain, as well as recent technological advances that can be employed to answer them.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.