Evidence map›Paper›PMID 25436819›Full record

Trial reportJournal of acquired immune deficiency syndromes (1999)2014

Pregnancy intent among a sample of recently diagnosed HIV-positive women and men practicing unprotected sex in Cape Town, South Africa.

Joanne E Mantell, Theresa M Exner, Diane Cooper, Dan Bai, Cheng-Shiun Leu, Susie Hoffman, Landon Myer, Jennifer Moodley, Elizabeth A Kelvin, Debbie Constant and 3 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of acquired immune deficiency syndromes (1999), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03617874 (PC4PrEP), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03617874 nacompletednot on this mapstarted 2020, after this paper: background citation

PC4PrEP: Integrating Pre-Exposure Prophylaxis (PrEP) Into Primary Care

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2020 to 2022Enrolled22ConditionsHuman Immunodeficiency Virus TransmissionArmsPC4PrEP- Intervention Clinics, Standard of Care Clinics
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Reproductive Desire in Women Living with HIV/AIDS with Serodiscordant Partners.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Joanne E Mantell*Division of Gender, Sexuality and Health, HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Department of Psychiatry, Columbia University, New York, NY; †Women's Health Research Unit, University of Cape Town School of Public Health and Family Medicine, Cape Town, South Africa; ‡Departments of Biostatistics and Epidemiology, Joseph Mailman School of Public Health, Columbia University, New York, NY; §Division of Epidemiology and Biostatistics, University of Cape Town School of Public Health and Family Medicine, Cape Town, South Africa; ‖Epidemiology and Biostatistics Program, The City University of New York School of Public Health, Hunter College, New York, NY; ¶City of Cape Town Department of Health, Cape Town, South Africa; and #University of Cape Town School of Public Health and Family Medicine, Cape Town, South Africa.
Theresa M Exner
Diane Cooper
Dan Bai
Cheng-Shiun Leu
Susie Hoffman
Landon Myer
Jennifer Moodley
Elizabeth A Kelvin
Debbie Constant
Karen Jennings
Virginia Zweigenthal
Zena A Stein
University of Cape Town · ZANew York Psychoanalytic Society and Institute · USColumbia University · USCity of Cape Town · ZACity University of New York · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
A Structural Intervention To Integrate Reproductive Health Into HIV CareR01MH078770 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANTELL, JOANNE ELLEN · 2007 to 2011
$2.5M
NIMH NIH HHS P30 MH043520NIMH NIH HHS P30 MH43520NIMH NIH HHS R01 MH 078770NIMH NIH HHS R01 MH078770
6 · The paper itself

Abstract

backgroundSexual and reproductive health (SRH) services for HIV-positive women and men often neglect their fertility desires. We examined factors associated with pregnancy intent among recently diagnosed HIV-positive women (N = 106) and men (N = 91) who reported inconsistent condom use and were enrolled in an SRH intervention conducted in public sector HIV care clinics in Cape Town.

methodsParticipants were recruited when receiving their first CD4 results at the clinic. All reported unprotected sex in the previous 3 months. Logistic regression identified predictors of pregnancy intent for the total sample and by gender.

resultsAbout three fifths of men and one fifth of women reported intent to conceive in the next 6 months. In the full-sample multiple regression analysis, men [adjusted odds ratio (AOR = 6.62)] and those whose main partner shared intent to conceive (AOR = 3.80) had significantly higher odds of pregnancy intent; those with more years of education (AOR = 0.81) and more biological children (AOR = 0.62) had lower odds of intending pregnancy. In gender-specific analyses, partner sharing pregnancy intent was positively associated with intent among both men (AOR = 3.53) and women (AOR = 13.24). Among men, odds were lower among those having more biological children (AOR = 0.71) and those unemployed (AOR = 0.30). Among women, relying on hormonal contraception was negatively associated with intent (AOR = 0.08), and main partner knowing her HIV status (AOR = 5.80) was positively associated with intent to conceive.

conclusionsFindings underscore the importance of providing integrated SRH services, and we discuss implications for clinical practice and care.

Indexed as

IntentionAdolescentAdultAnti-HIV AgentsFemaleHIV InfectionsHumansMaleMiddle AgedPovertyPregnancyPrevalenceSex FactorsSexual BehaviorSouth AfricaUnsafe SexAnti-HIV Agents

Identifiers

PMID25436819
PMCPMC4251915
OpenAlexW2073576630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.