Evidence map›Paper›PMID 25436655›Full record

Trial reportSensors (Basel, Switzerland)2014

Micro-Raman spectroscopy for monitoring changes in periodontal ligaments and gingival crevicular fluid.

Carlo Camerlingo, Fabrizia d'Apuzzo, Vincenzo Grassia, Letizia Perillo, Maria Lepore

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Sensors (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Sensors (Basel, Switzerland) · 2022
    Article
  6. Review
  7. Article
  8. Raman Spectroscopy: A Potential Diagnostic Tool for Oral Diseases.Frontiers in cellular and infection microbiology · 2022
    Review
  9. Article
  10. Review
  11. Review
  12. Infection ofCells · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carlo CamerlingoCNR-SPIN, Istituto Superconduttori, Materiali Innovativi e Dispositivi, via Campi Flegrei 34, Pozzuoli 80078, Italy. carlo.camerlingo@spin.cnr.it.
Fabrizia d'ApuzzoDip. Multidisciplinare di Specialità Medico-Chirurgiche e Odontoiatriche, Seconda Università di Napoli, via L. De Crecchio 6, Napoli 80138, Italy. fabriziadapuzzo@gmail.com.
Vincenzo GrassiaDip. Multidisciplinare di Specialità Medico-Chirurgiche e Odontoiatriche, Seconda Università di Napoli, via L. De Crecchio 6, Napoli 80138, Italy. grassiavincenzo@libero.it.
Letizia PerilloDip. Multidisciplinare di Specialità Medico-Chirurgiche e Odontoiatriche, Seconda Università di Napoli, via L. De Crecchio 6, Napoli 80138, Italy. letizia.perillo@unina2.it.
Maria LeporeDip. di Medicina Sperimentale, Seconda Università di Napoli, S. Maria di Costantinopoli 16, Napoli 80138, Italy. maria.lepore@unina2.it.
University of Naples Federico II · ITSuperconducting and other Innovative Materials and Devices Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Micro-Raman Spectroscopy is an efficient method for analyzing biological specimens due to its sensitivity to subtle chemical and structural changes. The aim of this study was to use micro-Raman spectroscopy to analyze chemical and structural changes in periodontal ligament after orthodontic force application and in gingival crevicular fluid in presence of periodontal disease. The biopsy of periodontal ligament samples of premolars extracted for orthodontic reasons and the gingival crevicular fluid samples collected by using absorbent paper cones; were analyzed by micro-Raman spectroscopy. Changes of the secondary protein structure related to different times of orthodontic force application were reported; whereas an increase of carotene was revealed in patients affected by periodontal inflammation.

Indexed as

Tooth Movement TechniquesAdolescentAdultDental Stress AnalysisFemaleGingival Crevicular FluidHumansMalePeriodontal LigamentProteinsProtein Structure, SecondarySpectrum Analysis, RamanYoung AdultProteins

Identifiers

PMID25436655
PMCPMC4299027
OpenAlexW2104253204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.