Evidence map›Paper›PMID 25436184›Full record

ArticleWorld journal of translational medicine2013

Molecular recognition of live

Diane Turek, Dimitri Van Simaeys, Judith Johnson, Ismail Ocsoy, Weihong Tan

Open access · hybridAbstract read
In one paragraph

Article in World journal of translational medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Selective Capture and Identification of Methicillin-ResistantInternational journal of molecular sciences · 2021
    Article
  10. Binding Characteristics Study of DNA based Aptamers forMolecules (Basel, Switzerland) · 2021
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Diane TurekShands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611, United States.
Dimitri Van SimaeysShands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611, United States.
Judith JohnsonEmerging Pathogens Institute, University of Florida, Gainesville, FL 32611, United States.
Ismail OcsoyDepartment of Chemistry, Center for Research at Bio/Nano Interface, University of Florida, Gainesville, FL 32611, United States.
Weihong TanShands Cancer and Genetic Research Center, Department of Physiology and Functional Genomics, University of Florida, Gainesville, FL 32611, United States.
University of Florida Health · US

Funding

Development of molecular probes for biomedical applicationsR01GM079359 · NIGMS · UNIVERSITY OF FLORIDA · PI TAN, WEIHONG · 2007 to 2016
$2.3M
NIGMS NIH HHS R01 GM079359
6 · The paper itself

Abstract

aimTo generate DNA-aptamers binding to

methodsThe Cell-Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology was used to run the selection against

resultsDuring the cell-SELEX selection process, 17 rounds were necessary to generate enrichment of the pool. While the selection was run using fixed cells, it was shown that the binding of the pools with live cells was giving similar results. After sequencing and analysis of the two last pools, four sequences were identified to be aptamer candidates. The characterization of those aptamers showed that based on their

conclusionA total of four aptamers that bind to MRSA were obtained with

Indexed as

AptamerCell recognitionGram-positve bacteriaMethicillin-resistant Staphylococcus aureus

Identifiers

PMID25436184
PMCPMC4244701
OpenAlexW2081251468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.