Evidence map›Paper›PMID 25436126›Full record

ArticleJournal of gastrointestinal oncology2014

The association of H. pylori and colorectal adenoma: does it exist in the US Hispanic population?

Shruti Patel, Seth Lipka, Huafeng Shen, Alex Barnowsky, Jeff Silpe, Josh Mosdale, Qinshi Pan, Svetlana Fridlyand, Anuradha Bhavsar, Albin Abraham and 3 more

Open access · greenAbstract read
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In one paragraph

Article in Journal of gastrointestinal oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Association BetweenFrontiers in medicine · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. EClinicalMedicine · 2025
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  7. Ethnic Disparities in Early-Onset Gastric Cancer Persist across Rural-Urban Geographies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  8. The Association between Helicobacter pylori and Colorectal Neoplasia.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Article
  9. Article
  10. World journal of gastroenterology · 2020
    Article
  11. Association ofWorld journal of gastrointestinal oncology · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Przeglad gastroenterologiczny · 2019
    Article
  16. Article
  17. Article
  18. World journal of gastroenterology · 2017
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Shruti Patel1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Seth Lipka1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Huafeng Shen1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Alex Barnowsky1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Jeff Silpe1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Josh Mosdale1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Qinshi Pan1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Svetlana Fridlyand1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Anuradha Bhavsar1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Albin Abraham1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Prakash Viswanathan1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Paul Mustacchia1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Bhuma Krishnamachari1 Department of Medicine, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 2 Division of Digestive Diseases and Nutrition, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 3 Department of Medicine, Division of Gastroenterology, Nassau University Medical Center Associated with North Shore-Long Island Jewish Health Care System, East Meadow, NY, USA ; 4 Department of Medicine, Academic Medicine Scholars Program, NYIT College of Osteopathic Medicine, Old Westbury, NY, USA.
Northwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough data on the association between colorectal adenomas and Helicobacter pylori (H. pylori) exists in White and Black patients, there is no data on this association in a US Hispanic population. Our aim was to study the association of adenoma detection and biopsy proven H. pylori infection in a cohort of US Hispanics.

methodsData were collected from Nassau University Medical Center, a 530-bed tertiary care teaching hospital in East Meadow, New York. Patients who underwent both an esophagogastroduodenoscopy (EGD) and colonoscopy from July 2009 to March 2011 were pulled from an electronic database. A total of 1,737 patients completed colonoscopies during this time with 95 excluded: 17 inflammatory bowel disease, 12 malignancy, 22 prior history of colorectal adenoma, and 44 incomplete. Among the colonoscopies, 799 patients had EGD's performed prior to colonoscopies that were eligible for our study.

resultsH. pylori prevalence was highest in Hispanics 40.9%, followed by Blacks 29.1% (OR 0.59, 95% CI: 0.42-0.84), then Whites 7.9% (OR 0.12, 95% CI: 0.06-0.24). The adenoma detection rate was significantly higher in Whites 23.2% and Blacks 21.8% compared to Hispanics 14.5%, P=0.0002 respectively. Smoking and alcohol were lower in the H. pylori group, 18.6% (n=44) vs. 26.1% (n=147) for smoking (P=0.02) and 14.4% (n=34) vs. 19% (n=107) for alcohol (P=0.12), respectively. There was no evidence in the Hispanics for an association between adenoma detection and H. pylori infection. Furthermore size, location, and multiple polyps did not differ between the two groups.

conclusionsWhile data has shown an association between H. pylori and colorectal adenomas, we did not find this in our Hispanic population. With the growing population of Hispanics in the U.S, large scale studies are needed to conclusively characterize the role of H. pylori infection in colorectal adenoma and adenocarcinoma in this group of patients.

Indexed as

colorectal adenomacolorectal cancerHispanicneoplasia

Identifiers

PMID25436126
PMCPMC4226815
OpenAlexW2143382269

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.