ReviewGastroenterology and hepatology from bed to bench2014
Potential treatment of inflammatory bowel disease: a review of helminths therapy.
Review in Gastroenterology and hepatology from bed to bench, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Parasite Cystatin: Immunomodulatory Molecule with Therapeutic Activity against Immune Mediated Disorders.Pathogens (Basel, Switzerland) · 2020Review
- Evaluation of long-term consumption of omeprazole disadvantages: a network analysis.Gastroenterology and hepatology from bed to bench · 2020Article
- Introducing GATA3 as a prominent player in Crohn's disease.Gastroenterology and hepatology from bed to bench · 2020Article
- Potential Vaccines for Treating Crohn's DiseaseIranian biomedical journal · 2020Review
- Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model.Scientific reports · 2019Article
- Interleukin 33 regulates gene expression in intestinal epithelial cells independently of its nuclear localization.Cytokine · 2018Article
- Article
- Immunocompromised patients with pulmonary tuberculosis; a susceptible group to intestinal parasites.Gastroenterology and hepatology from bed to bench · 2018Article
- Evaluation of IL-12A, IL-12B, IL-23A and IL-27 mRNA expression level genes in peripheral mononuclear cells of inflammatory bowel disease patients in an Iranian population.Gastroenterology and hepatology from bed to bench · 2018Article
- Influence of working in auto factory on gastroesophageal reflux disease.Gastroenterology and hepatology from bed to bench · 2018Article
- Evaluation of the cardiovascular risk in patients with biliary stones: a descriptive cross-sectional study.Gastroenterology and hepatology from bed to bench · 2018Article
- Determining the degree of adherence to treatment in inflammatory bowel disease patients.Gastroenterology and hepatology from bed to bench · 2018Article
- Apoptosis markers of circulating leukocytes are associated with the clinical course of inflammatory bowel disease.Gastroenterology and hepatology from bed to bench · 2018Article
- Fibroblast-myofibroblast crosstalk after exposure to mesenchymal stem cells secretome.Gastroenterology and hepatology from bed to bench · 2018Article
- Inducible nitric oxide synthase as a potential blood-based biomarker in inflammatory bowel diseases.Gastroenterology and hepatology from bed to bench · 2018Article
- Development of experimental fibrotic liver diseases animal model by Carbon Tetracholoride.Gastroenterology and hepatology from bed to bench · 2017Article
- Common and differential genetically pathways between ulcerative colitis and colon adenocarcinoma.Gastroenterology and hepatology from bed to bench · 2017Article
- Detailed analysis of total colectomy on health-related quality of life in adult patients with ulcerative colitis.Gastroenterology and hepatology from bed to bench · 2017Article
- Introduction of inflammatory bowel disease biomarkers panel using protein-protein interaction (PPI) network analysis.Gastroenterology and hepatology from bed to bench · 2016Article
- Recent insights into the molecular pathogenesis of Crohn's disease: a review of emerging therapeutic targets.Clinical and experimental gastroenterology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An inflammatory bowel disease (IBD) is most common in highly industrialized Western countries but uncommon in less developed areas of the world where helminths are frequent. The hygiene hypothesis proposes that the recent increase in allergic and autoimmune diseases is due to modern highly hygienic life styles and medical conditions. Loss of routine exposure to parasitic helminths, as a result of increasing lifestyle-associated factors, may be one factor leading to the increased disease prevalence. In animal models and clinical trials of IBD, gastrointestinal nematodes colonization suppresses intestinal inflammation through multiple mechanisms including induction of innate and adaptive regulatory circuits. Studies using helminths like Trichuris suis or Necator americanus showed that these helminths are safe and may be effective therapeutic approaches for the control of IBD and other immune diseases. The aim of present review was to exploring the therapeutic use of helminths for the control of IBD.
Indexed as
Identifiers
25436093PMC4017549W1530611653What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.