ArticleInternational journal of endocrinology2014
Determinants of Vitamin D Levels in Italian Children and Adolescents: A Longitudinal Evaluation of Cholecalciferol Supplementation versus the Improvement of Factors Influencing 25(OH)D Status.
Article in International journal of endocrinology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A systematic review of vitamin D status in southern European countries.European journal of nutrition · 2018Pooled it
- Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders.Mini reviews in medicinal chemistry · 2024Review
- Impact of COVID-19 Pandemic and Associated Restrictions on Vitamin D Status in a Large Cohort of Italian Children and Adolescents.Medicina (Kaunas, Lithuania) · 2023Article
- Prevalence and determinants of vitamin D deficiency in Iranian children and adolescents: the CASPIAN-V study.Journal of diabetes and metabolic disorders · 2021Article
- Seasonal Changes in Vitamin D Levels of Healthy Children in Mid-Latitude, Asian Urban Area.Pediatric gastroenterology, hepatology & nutrition · 2021Article
- The Role of Micronutrients in Support of the Immune Response against Viral Infections.Nutrients · 2020Review
- Effect of vitamin D3 seasonal supplementation with 1500 IU/day in north Italian children (DINOS study).Italian journal of pediatrics · 2019Article
- Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians.Italian journal of pediatrics · 2018Review
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- Severe vitamin D deficiency in patients with Kawasaki disease: a potential role in the risk to develop heart vascular abnormalities?Clinical rheumatology · 2016Article
- Bone Mineral Status in Children and Adolescents with Klinefelter Syndrome.International journal of endocrinology · 2016Article
- Serum NT-proBNP Levels Are Not Related to Vitamin D Status in Young Patients with Congenital Heart Defects.Disease markers · 2016Article
- Determinants of vitamin d levels in children and adolescents with down syndrome.International journal of endocrinology · 2015Article
- Vitamin D deficiency among pediatric osteoarticular tuberculosis patients.Journal of clinical orthopaedics and traumaArticle
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Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective. This paper aims to assess 25(OH)D levels in Italian children and adolescents identifying risk factors for 25(OH)D deficiency and to evaluate whether a normal 25(OH)D value can be restored in 25(OH)D-deficient patients. Methods. We evaluated 25(OH)D levels in 679 Italian children and adolescents (≤10, 11-20, 21-30, and >30 ng/mL were defined as severe deficiency, deficiency, insufficiency, and sufficiency, resp.). Of these, 365 25(OH)D-deficient were followed up for 1 year; 205 were treated with cholecalciferol (Arm A: 400 I.U.) and 160 by improving the environmental variables influencing 25(OH)D levels (Arm B). Results. At cross-sectional evaluation, 11.3% showed sufficiency, 30.0% insufficiency, and 58.7% 25(OH)D deficiency. Mean 25(OH)D was 19.08 ± 8.44 ng/mL. At the enrollment time (T 0), no difference was found between Arms A and B with respect to distribution and 25(OH)D levels. At end time (T 1) 26.0% (29.7% in Arm A versus 20.6% in Arm B) showed sufficiency, 38.4% (42.0% versus 34.4%) insufficiency, and 35.6% (28.3% versus 45.0%) 25(OH)D deficiency. Mean 25(OH)D level was 23.71 ± 6.83 ng/mL. Conclusions. Neither changes of lifestyle nor 400 I.U. cholecalciferol supplementation alone appears to be sufficient to restore adequate 25(OH)D levels.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.