Evidence map›Paper›PMID 25435644›Full record

ArticleOrganometallics2014

Organometallic Titanocene-Gold Compounds as Potential Chemotherapeutics in Renal Cancer. Study of their Protein Kinase Inhibitory Properties.

Jacob Fernández-Gallardo, Benelita T Elie, Florian J Sulzmaier, Mercedes Sanaú, Joe W Ramos, María Contel

Open access · bronzeAbstract read
In one paragraph

Article in Organometallics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Mapping the Landscape of Global Anticancer Organometallics Research: A Systematic Review.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Pooled it
  2. Article
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  5. Cancer 3D Models for Metallodrug Preclinical Testing.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jacob Fernández-GallardoDepartment of Chemistry, Brooklyn College and The Graduate Center, The City University of New York , Brooklyn, New York 11210, United States.
Benelita T ElieDepartment of Chemistry, Brooklyn College and The Graduate Center, The City University of New York , Brooklyn, New York 11210, United States.
Florian J SulzmaierCancer Biology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa , Honolulu, Hawaii 96813, United States.
Mercedes SanaúDepartamento de Química Inorgánica, Universidad de Valencia , Burjassot, Valencia, 46100, Spain.
Joe W RamosCancer Biology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa , Honolulu, Hawaii 96813, United States.
María ContelDepartment of Chemistry, Brooklyn College and The Graduate Center, The City University of New York , Brooklyn, New York 11210, United States ; Cancer Biology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa , Honolulu, Hawaii 96813, United States.
University of Hawaii Cancer CenterBrooklyn College · USThe Graduate Center, CUNY · USUniversitat de València · ES

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
Titanium-gold-based chemotherapeutics for prostate and kidney cancerSC1CA182844 · NCI · BROOKLYN COLLEGE · PI CONTEL, MARIA · 2013 to 2016
$1.4M
RSK-2 regulates integrin-mediated adhesion and migrationR01GM088266 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI RAMOS, JOE WILLIAM · 2010 to 2013
$1.4M
NCI NIH HHS P30 CA071789NCI NIH HHS SC1 CA182844NIGMS NIH HHS R01 GM088266
6 · The paper itself

Abstract

Early-late transition metal TiAu

Identifiers

PMID25435644
PMCPMC4245150
OpenAlexW2329166030

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.