Evidence map›Paper›PMID 25435104›Full record

ArticleChild abuse & neglect2015

Maternal intimate partner violence exposure, child cortisol reactivity and child asthma.

Megan H Bair-Merritt, Kristin Voegtline, Sharon R Ghazarian, Douglas A Granger, Clancy Blair, Family Life Project Investigators, Sara B Johnson

Abstract read
In one paragraph

Article in Child abuse & neglect, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The effects of violence and related stress on asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Review
  7. Maternal-infant interaction quality is associated with child NR3C1 CpG site methylation at 7 years of age.American journal of human biology : the official journal of the Human Biology Council · 2023
    Article
  8. Child maltreatment and asthma.Pediatric pulmonology · 2022
    Review
  9. Review
  10. Exposure to Violence, Psychosocial Stress, and Asthma.American journal of respiratory and critical care medicine · 2020
    Review
  11. Family Matters: Research on Family Ties and Health, 2010-2020.Journal of marriage and the family · 2020
    Article
  12. State-of-the-Science Review of Non-Chemical Stressors Found in a Child's Social Environment.International journal of environmental research and public health · 2019
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan H Bair-MerrittDivision of General Pediatrics, Boston Medical Center, 88 East Newton Street, Vose 305, Boston, MA 02118, USA.
Kristin VoegtlineDepartment of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA.
Sharon R GhazarianJohns Hopkins School of Medicine, 200 North Wolfe Street, Division of General Pediatrics, Baltimore, MD 21287, USA.
Douglas A GrangerInstitute for Interdisciplinary Salivary Bioscience Research, Arizona State University, 550 East Orange Street, Tempe, AZ 85287, USA; School of Nursing, Johns Hopkins, 525 North Wolfe Street, Baltimore, MD 21205, USA; Department of Applied Psychology, New York University, 246 Greene Street, New York, NY 10003, USA.
Clancy BlairDivision of General Pediatrics, Boston Medical Center, 88 East Newton Street, Vose 305, Boston, MA 02118, USA; Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA; Johns Hopkins School of Medicine, 200 North Wolfe Street, Division of General Pediatrics, Baltimore, MD 21287, USA; Institute for Interdisciplinary Salivary Bioscience Research, Arizona State University, 550 East Orange Street, Tempe, AZ 85287, USA; School of Nursing, Johns Hopkins, 525 North Wolfe Street, Baltimore, MD 21205, USA; Department of Applied Psychology, New York University, 246 Greene Street, New York, NY 10003, USA.
Family Life Project Investigators
Sara B JohnsonDepartment of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, 615 North Wolfe Street, Baltimore, MD 21205, USA; Johns Hopkins School of Medicine, 200 North Wolfe Street, Division of General Pediatrics, Baltimore, MD 21287, USA.

Funding

Temperment, Psychobiological, and Cognitive PredictorsP01HD039667 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI VERNON-FEAGANS, LYNNE · 2002 to 2011
$29.1M
Environment, Psychosocial Stress and Self-regulatory DevelopmentK01DA027229 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JOHNSON, SARA B. · 2010 to 2014
$692k
Organizational and activational effects of sex steroids on child self-regulationK99HD077058 · NICHD · JOHNS HOPKINS UNIVERSITY · PI VOEGTLINE, KRISTIN M · 2014 to 2015
$253k
NICHD NIH HHS K99 HD077058NICHD NIH HHS P01 HD039667NICHD NIH HHS P01 HD39667NIDA NIH HHS K01 DA027229
6 · The paper itself

Abstract

Psychosocial stressors like intimate partner violence (IPV) exposure are associated with increased risk of childhood asthma. Longitudinal studies have not investigated the role of hypothalamic-pituitary-adrenal (HPA) axis reactivity (and associated alterations in cortisol release) in the child IPV exposure-asthma association. We sought to investigate this association, and to assess whether this relationship differs by child HPA reactivity. This secondary analysis used longitudinal cohort data from the Family Life Project. Participants included 1,292 low-income children and mothers; maternal interview and child biomarker data, including maternal report of IPV and child asthma, and child salivary cortisol obtained with validated stress reactivity paradigms, were collected when the child was 7, 15, 24, 35, and 48 months. Using structural equation modeling, maternal IPV when the child was 7 months of age predicted subsequent reports of childhood asthma (B=0.18, p=.002). This association differed according to the child's HPA reactivity status, with IPV exposed children who were HPA reactors at 7 and 15 months of age--defined as a ≥10% increase in cortisol level twenty minutes post peak arousal during the challenge tasks and a raw increase of at least .02μg/dl--being significantly at risk for asthma (7 months: B=0.17, p=.02; 15 months: B=0.17, p=.02). Our findings provide support that children who are physiologically reactive are the most vulnerable to adverse health outcomes when faced with environmental stressors.

Indexed as

AdultAsthmaBlack or African AmericanChild, PreschoolDepressionFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemInfantInterviews as TopicIntimate Partner ViolenceLongitudinal StudiesMaleMother-Child RelationsMothersHydrocortisoneAsthmaCortisolIntimate partner violenceLongitudinal

Identifiers

PMID25435104
PMCPMC4446253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.