ArticleScientific reports2014
A genome scan revealed significant associations of growth traits with a major QTL and GHR2 in tilapia.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 73 citations in OpenAlex.
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- RNA-seq and whole-genome re-sequencing reveal Micropterus salmoides growth-linked gene and selection signatures under carbohydrate-rich diet and varying temperature.Scientific reports · 2024Article
- Animal board invited review: Widespread adoption of genetic technologies is key to sustainable expansion of global aquaculture.Animal : an international journal of animal bioscience · 2022Review
- Unraveling the complex genetic basis of growth in New Zealand silver trevally (Pseudocaranx georgianus).G3 (Bethesda, Md.) · 2022Article
- Genetic and epigenetic regulation of growth, reproduction, disease resistance and stress responses in aquaculture.Frontiers in genetics · 2022Review
- Mapping of quantitative trait loci underlying a magic trait in ongoing ecological speciation.BMC genomics · 2021Article
- Function of Circular RNAs in Fish and Their Potential Application as Biomarkers.International journal of molecular sciences · 2021Review
- A first genetic linage map construction and QTL mapping for growth traits in Larimichthys polyactis.Scientific reports · 2020Article
- Genetic analysis of body weight in wild populations of medaka fish from different latitudes.PloS one · 2020Article
- Construction of a high-density genetic linkage map and mapping of quantitative trait loci for growth-related traits in silver carp (Hypophthalmichthys molitrix).Scientific reports · 2019Article
- QTL Mapping for Red Blotches in Malaysia Red Tilapia (Oreochromis spp.).Marine biotechnology (New York, N.Y.) · 2019Article
- Genome Scan for Genomic Regions and Genes Associated with Growth Trait in Pacific White Shrimp Litopeneaus vannamei.Marine biotechnology (New York, N.Y.) · 2019Article
- Transcriptome Analysis Identified Genes for Growth and Omega-3/-6 Ratio in Saline Tilapia.Frontiers in genetics · 2019Article
- Identification of novel genes significantly affecting growth in catfish through GWAS analysis.Molecular genetics and genomics : MGG · 2018Article
- A high-resolution genetic linkage map and QTL fine mapping for growth-related traits and sex in the Yangtze River common carp (Cyprinus carpio haematopterus).BMC genomics · 2018Article
- Mapping QTL for Omega-3 Content in Hybrid Saline Tilapia.Marine biotechnology (New York, N.Y.) · 2018Article
- Differential gene expression and SNP association between fast- and slow-growing turbot (Scophthalmus maximus).Scientific reports · 2017Article
- Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research.BMC genomics · 2017Review
- Copy Number Variations in Tilapia Genomes.Marine biotechnology (New York, N.Y.) · 2017Article
- An ultra-high density linkage map and QTL mapping for sex and growth-related traits of common carp (Cyprinus carpio).Scientific reports · 2016Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Growth is an important trait in animal breeding. However, the genetic effects underpinning fish growth variability are still poorly understood. QTL mapping and analysis of candidate genes are effective methods to address this issue. We conducted a genome-wide QTL analysis for growth in tilapia. A total of 10, 7 and 8 significant QTLs were identified for body weight, total length and standard length at 140 dph, respectively. The majority of these QTLs were sex-specific. One major QTL for growth traits was identified in the sex-determining locus in LG1, explaining 71.7%, 67.2% and 64.9% of the phenotypic variation (PV) of body weight, total length and standard length, respectively. In addition, a candidate gene GHR2 in a QTL was significantly associated with body weight, explaining 13.1% of PV. Real-time qPCR revealed that different genotypes at the GHR2 locus influenced the IGF-1 expression level. The markers located in the major QTL for growth traits could be used in marker-assisted selection of tilapia. The associations between GHR2 variants and growth traits suggest that the GHR2 gene should be an important gene that explains the difference in growth among tilapia species.
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