ArticleBrain : a journal of neurology2015
Motion area V5/MT+ response to global motion in the absence of V1 resembles early visual cortex.
Article in Brain : a journal of neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Generalisation of training-induced recovery in occipital stroke: neurochemical and fMRI correlates.bioRxiv : the preprint server for biology · 2026Article
- Direction selectivity in naturalistic action observation: distributed representations across the action observation network.Brain structure & function · 2026Article
- No Unique Magnocellular Facilitation in Parafoveal Processing: A Combined EEG and Eye Tracking Study.Neurobiology of language (Cambridge, Mass.) · 2026Article
- No facilitatory effects of transcranial random noise stimulation on motion processing: A registered report.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Voxel-Based Lesion-Symptom Mapping Localizes Residual Visual Function in Hemianopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Role of Population Receptive Field Sizes in Higher-Order Visual Dysfunction.Current neurology and neuroscience reports · 2024Review
- A clinico-anatomical dissection of the magnocellular and parvocellular pathways in a patient with the Riddoch syndrome.Brain structure & function · 2024Article
- Looming Angry Faces: Preliminary Evidence of Differential Electrophysiological Dynamics for Filtered Stimuli via Low and High Spatial Frequencies.Brain sciences · 2024Article
- Preserved motion perception and the density of cortical projections to V5 in homonymous hemianopia.Brain communications · 2024Article
- Neural patterns of conscious visual awareness in the Riddoch syndrome.Journal of neurology · 2023Article
- White matter plasticity following cataract surgery in congenitally blind patients.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Convolutional neural networks for vision neuroscience: significance, developments, and outstanding issues.Frontiers in computational neuroscience · 2023Review
- Visual orientation discrimination skills are tightly linked with specific aspects of human intelligence.PloS one · 2023Article
- A Scientific Approach to Conscious Experience, Introspection, and Unconscious Processing: Vision and Blindsight.Brain sciences · 2022Review
- Neural Mechanisms of Visual Field Recovery after Perceptual Training in Cortical Blindness.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Network Localization of Unconscious Visual Perception in Blindsight.Annals of neurology · 2022Article
- High-definition transcranial direct current stimulation of the left middle temporal complex does not affect visual motion perception learning.Frontiers in neuroscience · 2022Article
- Visual Motion Coherence Responses in Human Visual Cortex.Frontiers in neuroscience · 2022Article
- Contribution of the slow motion mechanism to global motion revealed by an MAE technique.Scientific reports · 2021Article
- Visual Field Test With Gaze Check Tasks: Application in a Homonymous Hemianopic Patient Unaware of the Visual Defects.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Motion area V5/MT+ shows a variety of characteristic visual responses, often linked to perception, which are heavily influenced by its rich connectivity with the primary visual cortex (V1). This human motion area also receives a number of inputs from other visual regions, including direct subcortical connections and callosal connections with the contralateral hemisphere. Little is currently known about such alternative inputs to V5/MT+ and how they may drive and influence its activity. Using functional magnetic resonance imaging, the response of human V5/MT+ to increasing the proportion of coherent motion was measured in seven patients with unilateral V1 damage acquired during adulthood, and a group of healthy age-matched controls. When V1 was damaged, the typical V5/MT+ response to increasing coherence was lost. Rather, V5/MT+ in patients showed a negative trend with coherence that was similar to coherence-related activity in V1 of healthy control subjects. This shift to a response-pattern more typical of early visual cortex suggests that in the absence of V1, V5/MT+ activity may be shaped by similar direct subcortical input. This is likely to reflect intact residual pathways rather than a change in connectivity, and has important implications for blindsight function. It also confirms predictions that V1 is critically involved in normal V5/MT+ global motion processing, consistent with a convergent model of V1 input to V5/MT+. Historically, most attempts to model cortical visual responses do not consider the contribution of direct subcortical inputs that may bypass striate cortex, such as input to V5/MT+. We have shown that the signal change driven by these non-striate pathways can be measured, and suggest that models of the intact visual system may benefit from considering their contribution.
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