Trial reportContemporary clinical trials2015
Motivators and barriers to Latinas' participation in clinical trials: the role of contextual factors.
Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04800432 (ADAPT+), which is not on this map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ADAPT+: Optimizing an Intervention to Promote Healthy Behaviors in Rural, Latino Youth With Obesity and Their Parents, Using Mindfulness Strategies
Who cites it
30 citing papers in PubMed.
- Email-Based Recruitment Into the Health eHeart Study: Cohort Analysis of Invited Eligible Patients.Journal of medical Internet research · 2023Trial
- Effectiveness of Recruitment Strategies of Latino Smokers: Secondary Analysis of a Mobile Health Smoking Cessation Randomized Clinical Trial.Journal of medical Internet research · 2022Trial
- Feasibility and Effectiveness of Recruiting Latinos inInternational journal of environmental research and public health · 2021Trial
- Empowering Latina breast cancer patients to make informed decisions about clinical trials: a pilot study.Translational behavioral medicine · 2018Trial
- Long-term Diet and Biomarker Changes after a Short-term Intervention among Hispanic Breast Cancer Survivors: The ¡Cocinar Para Su Salud! Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016Trial
- Barriers and strategies for recruitment of pregnant women in contemporary longitudinal birth cohort studies.BMC medical research methodology · 2025Article
- Después del Cáncer: a qualitative exploration of navigating survivorship as a Latino couple following a breast cancer diagnosis.Journal of cancer survivorship : research and practice · 2025Article
- The Impact of Insider Researcher Trainees in Recruiting and Retaining Latinx in an Outdoor Health Promotion Research Study.Journal of racial and ethnic health disparities · 2024Article
- Factors affecting the recruitment of Hispanic/Latinx American older adults in clinical trials in the United States: A scoping review.Journal of the American Geriatrics Society · 2023Article
- Willingness to participate in various nontherapeutic cancer research activities among urban and rural African American and Latinx healthy volunteers.Cancer causes & control : CCC · 2022Article
- Barriers for cancer clinical trial enrollment: A qualitative study of the perspectives of healthcare providers.Contemporary clinical trials communications · 2022Article
- Disparities in trial enrollment and outcomes of Hispanic adolescent and young adult acute lymphoblastic leukemia.Blood advances · 2022Article
- Article
- Cancer Epidemiology in Hispanic Populations: What Have We Learned and Where Do We Need to Make Progress?Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Review
- Equitable Representation of Latinos in Clinical Research Is Needed to Achieve Health Equity in Cancer Care.JCO oncology practice · 2022Article
- Motivators and barriers towards clinical research participation: A population-based survey from an Arab MENA country.PloS one · 2022Article
- Translation and validation of the greek version of a questionnaire measuring patient views on participation in clinical trials.BMC health services research · 2021Article
- Overcoming Disparities in Cancer: A Need for Meaningful Reform for Hispanic and Latino Cancer Survivors.The oncologist · 2021Review
- Design and rationale for ADAPT+: Optimizing an intervention to promote healthy behaviors in rural, Latino youth with obesity and their parents, using mindfulness strategies.Contemporary clinical trials · 2021Article
- Engaging Latinos in an Academic-Community Partnership in Montana through a Health Screening Event.American journal of health education · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
objectiveLatinas are underrepresented in clinical trials despite the rise in Hispanic population. This study examines the factors associated with Latinas' willingness to participate in preventive breast cancer randomized clinical trials (RCTs).
methodsWomen self-identifying as Latina, over age 40, with no prior history of breast cancer were eligible. Using the Behavior Model for Vulnerable Populations, we administered a survey (n=168) to assess predisposing (e.g., knowledge), enabling (e.g., trust) and need factors (e.g., risk perception). Intention to participate was defined using a lenient (maybe, probably or definitely) and a stringent criterion (probably and definitely). Chi-square tests and logistic regression models examined the associations of predisposing, enabling, and need factors with women's intentions to participate in RCTs.
resultsMost participants (74.9%) were monolingual Spanish-speaking immigrants. Most (83.9%) reported willing to participate in clinical trials using the lenient definition (vs. 43.1% under the stringent definition). Using the lenient definition, the odds of willing to participate in RCTs were significantly lower for unmarried women (OR=.25, 95% CI=.08-.79) and those with lower cancer risk perceptions (OR=.20, 95% CI=.06-.63), while being significantly higher for women with lower language acculturation (OR=6.2, 95% CI=1.8-20.9). Using the stringent definition, women who did not endorse a motivation to enroll to help family members (if they had cancer) had significantly lower odds to report intent (OR=.33, 95% CI=.13-.86).
conclusionMany RCTs may have limited generalizability due to the low representation of minorities. Culturally targeted interventions that address the importance of family for Latinos may ultimately increase their participation in RCTs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.