Evidence map›Paper›PMID 25433162›Full record

ReviewJournal of hepatology2015

Outcomes in liver transplantation: does sex matter?

Monika Sarkar, Kymberly D Watt, Norah Terrault, Marina Berenguer

Abstract readReview
In one paragraph

Review in Journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Sexual dimorphism in the liver.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  2. Article
  3. Article
  4. Sex and gender disparities in hepatocellular carcinoma: insights into risk, diagnosis, and therapeutic outcomes.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  5. [The importance of sex/gender for graft and patient survival].Innere Medizin (Heidelberg, Germany) · 2025
    Review
  6. Article
  7. Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  8. Article
  9. The Individual Impact of Machine Perfusion on Liver and Kidney on Donor Expansion in Simultaneous Liver and Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Women Are Also Disadvantaged in Accessing Transplant Outside the United States: Analysis of the Spanish Liver Transplantation Registry.Transplant international : official journal of the European Society for Organ Transplantation · 2024
    Article
  16. Article
  17. Article
  18. Sex differences in chronic liver disease and benign liver lesions.JHEP reports : innovation in hepatology · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Monika SarkarDivision of Gastroenterology and Hepatology, University of California, San Francisco, 513 Parnassus Avenue, S-357, San Francisco, CA 94143, USA. Electronic address: Monika.Sarkar@ucsf.edu.
Kymberly D WattDivision of Gastroenterology and Hepatology, Mayo Clinic and Foundation, 200 First St, Rochester, MN 55905, USA.
Norah TerraultDivision of Gastroenterology and Hepatology, University of California, San Francisco, 513 Parnassus Avenue, S-357, San Francisco, CA 94143, USA.
Marina BerenguerHepatology and Liver Transplantation Unit, La Fe Hospital and Ciberehd, Universidad Valencia, C/Bulevar Sur sn (Torre F-5) 46026 Valencia, Spain.

Funding

UCSF Liver Core CenterP30DK026743 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Holger Willenbring · 1986 to 2026
$30.7M
NIDDK NIH HHS L30 DK089607NIDDK NIH HHS P30 DK026743
6 · The paper itself

Abstract

A growing literature has highlighted important differences in transplant-related outcomes between men and women. In the United States there are fewer women than men on the liver transplant waitlist and women are two times less likely to receive a deceased or living-related liver transplant. Sex-based differences exist not only in waitlist but also in post-transplant outcomes, particularly in some specific liver diseases, such as hepatitis C. In the era of individualized medicine, recognition of these differences in the approach to pre and post-liver transplant care may impact short and long-term outcomes.

Indexed as

Liver TransplantationPostoperative ComplicationsEnd Stage Liver DiseaseFemaleGraft SurvivalHumansMaleOutcome Assessment, Health CarePerioperative PeriodSex FactorsTissue and Organ ProcurementWaiting ListsHepatitis C virusLiver allocationLiver transplantationMELD scoreQuality of lifeSexWaitlist outcomeWomen’s health

Identifiers

PMID25433162
PMCPMC5935797

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.